Modern instrumentation for Raman microspectroscopy and current techniques in analysis of spectral data provide new opportunities to study molecular interactions and dynamics at subcellular levels in biological systems. Implementation of biomolecular component analysis (BCA) to microRaman spectrometry provides basis for the emergence of Ramanomics, a new biosensing discipline with unprecedented ...

Understanding biomolecular systems is important both for the analysis of naturally occurring systems as well as for the design of new ones. However, mathematical tools for analysis of such complex systems are generally lacking. Here, we present an application of the method of sinusoidal-input describing function for the analysis of such a system. Using this technique, we approximate the input-o...

Incorporation of van der Waals interactions enables the continuum model of electrodiffusion in biomolecular system to avoid the artifacts of introducing a molecular surface and the painful task of the surface mesh generation. Calculation examples show that the electrostatics, diffusion-reaction kinetics, and molecular surface defined as an isosurface of a certain density distribution can be ext...

Control theory has been instrumental for the development of a number of engineering systems, including aerospace and transportation systems, robotics and intelligent machines, manufacturing chains, electrical, power, and information networks. In the past decade, the ability of engineering biomolecular networks has become a reality in the rising field of synthetic biology. Biomolecular networks ...

Control theory has been instrumental for the development of a number of engineering systems, including aerospace and transportation systems, robotics and intelligent machines, manufacturing chains, electrical, power, and information networks. In the past decade, the ability of engineering biomolecular networks has become a reality in the rising field of synthetic biology. Biomolecular networks ...

purpose: the distinction between the concepts of science and technology has made it necessary for economic and scientific policymakers to know the realms of these two areas. the relationship between the science and the technology is changing and also is variable depending on the circumstances, scientific areas, and from one time to another one. the current research aims at studying the growth t...

background and aims. digital imaging continues to gain acceptance in dentistry and video display used for this becomes important. the aim of this study was to assess the influence of the display monitor on observer performance on caries detection. materials and methods. artificial enamel lesions were created in 40 extracted teeth at random using 1/4 and 1/2 round burs. teeth were mounted in den...

The automotive industry is experiencing a remarkable move from the internal combustion engine (ICE) to an all-electric power platform. This natural shift essentially supported by electric drive development where wide-bandgap (WBG) materials are at center of this transformation. gallium nitride (GaN)- or silicon carbide (SiC)-based electronics taking place due theoretical limits Si MOSFETs that ...

A key problem in medical science and genomics is that of the efficient storage, processing and retrieval of genetic information and material. This paper presents an architecture for a Biomolecular Database system which provide a unique capability in genomics. It completely bypasses the usual transformation from biological material (genomic DNA and transcribed RNA) to digital media, as done in c...

ABSTRACT The currently hyped expectation of personalized medicine is often associated with just achieving the information technology led integration of biomolecular sequencing, expression and histopathological bioimaging data with clinical records at the individual patients' level as if the significant biomedical conclusions would be its more or less mandatory result. It remains a sad fact that...