PURPOSE To determine the in vitro effectiveness of Plantago major extract, along with two of its active components, aucubin and baicalein, on the inhibition of Candida albicans growth, biofilm formation, metabolic activity, and cell surface hydrophobicity. MATERIALS AND METHODS Twofold dilutions of P. major, aucubin, and baicalein were used to determine the minimum inhibitory concentration (M...

Bacterial biofilm formation can cause serious problems in clinical and industrial settings, which drives the development or screening of biofilm inhibitors. Some biofilm inhibitors have been screened from natural products or modified from natural compounds. Ginger has been used as a medicinal herb to treat infectious diseases for thousands of years, which leads to the hypothesis that it may con...

background. this study was designedaimed to investigate assess the antimicrobial antimicrobial eeffect of chlorhexidine (chx) on aggregatibacter a. actinomycetemcomitans biofilmss extracted isolated from subgingival plaque of periperi-iimplantitis lesions. methods. 13 thirteen participants patients requiring peri-implantitis treatment were consecutively selected and theirwere consecutively recr...

Background and objectives: Quercus brantii subsp. persica is used in folk medicine to treat infections in Iran. There is not available report on the anti-biofilm activity of Quercus brantii subsp. persica. The aim of the present study was to investigate the effects of Quercus brantii subsp. persica against bacterial biofilms. Methods: Eighty biofilm producing strains of Staphylococcus aureus, S...

BACKGROUND & OBJECTIVES Biofilms formed by pseudomonas aeruginosa lead to persistent infections. Use of antibiotics for the treatment of biofilm induced infection poses a threat towards development of resistance. Therefore, the research is directed towards exploring the property of antibiotics which may alter the virulence of an organism besides altering its growth. The aim of this study was to...

The aim of this study was to investigate the ability of hinokitiol to inhibit the formation of Candida biofilms. Biofilm inhibition was evaluated by quantification of the biofilm metabolic activity with XTT assay. Hinokitiol efficiently prevented biofilm formation in both fluconazole-susceptible and fluconazole-resistant strains of Candida species. We determined the expression levels of specifi...

An infection of the human oral cavity that is primarily fungal called Candida-associated denture stomatitis. Erythema palate and alveolar ridges are symptoms stomatitis, which a persistent inflammatory condition mucosa supporting dentures. So red pigment made by Serratia marcescens designated as prodigiosin was purified silica gel column chromatography with yield 3.7 g/l after being extracted a...

Recently, misuse or overuse of antibiotics has led to the antibiotic resistance problem, a global healthcare problem. Most virulence factors and biofilm formation in Pseudomonas aeruginosa are controlled by quorum sensing (QS). The inhibition QS system inhibitor molecules been suggested as novel alternative antivirulence approach which no need kill bacteria. In present study, inhibitory potenti...

The purpose of this study was to evaluate the inhibition of biofilm formation on newly developed coating materials with self-cleaning properties. A series of experimental coating materials containing fluoroalkylated acrylic acid oligomer (FAAO) were applied to resin composite substrates. The surfaces of the coating materials were analyzed by X-ray photoelectron spectroscopy (XPS) and contact an...

Current techniques for characterizing biofilm physiology lack the signal filtering capability required for quantifying signals associated with real time biologically active transport. Though a great deal was learned from previous investigations, no results have been reported on the characterization of in vivo, real time biofilm flux using non-invasive (non-destructive) techniques. This article ...