The authors measured concentrations of prostanoids (prostaglandin-like substances) in aqueous humor from normal pigmented rabbit eyes and from those subjected to argon laser photocoagulation of the iris. The predominant prostanoids quantitatively were prostaglandin E2 (PGE2), PGF2 alpha, and PGD2 with minor amounts of 6-keto-PGF1 alpha and thromboxane B2. In all cases, concentrations of prostan...

Aqueous humor was obtained by paracentesis at the time of cataract surgery from six patients with phacolytic glaucoma, diagnosed on the basis of acute unilateral open-angle glaucoma associated with an apparently leaking hypermature or mature cataract, and from six control patients with immature cataracts. Three of the latter had primary open-angle glaucoma. Quantities of heavy-molecular-weight ...

PURPOSE To determine the efficacy of intraoperative antibiotic use in irrigating solutions on aqueous humor contamination during phacoemulsification surgery and to evaluate the corresponding risk of postoperative endophthalmitis. METHODS 644 eyes of 640 patients who underwent phacoemulsification surgery with foldable intraocular lens (IOL) implantation were included in this study. Preoperativ...

LEARNING OBJECTIVES Upon completion of this activity, participants will be able to: 1. Create a staged management plan for patients with glaucoma. 2. list steps to take in the event that target IOP is not maintained. 3. Describe structural and functional bases of aqueous humor formation and outfl ow. 4. use aqueous humor pathophysiology to interpret ocular hypertension and the mechanisms of act...

In a continuing effort to develop a noninvasive means of monitoring glucose levels using the aqueous humor of the eye, a dual-wavelength system is developed to show that varying birefringence, similar to what is seen with a moving cornea, can be compensated. In this work, a dual-wavelength, closed-loop system is designed and a model is developed to extract the glucose concentration information....

5.2 Thermodynamic Considerations Solubilities and Aqueous Activity Coefficients of Organic Liquids Solubilities and Aqueous Activity Coefficients of Organic Solids Solubilities and Aqueous Activity Coefficients of Organic Gases Illustrative Example 5.1 : Deriving Liquid Aqueous Solubilities, Aqueous Activity CoefJicients, and Excess Free Energies in Aqueous Solution from Experimental Solubility...

PURPOSE To measure oxygen tension in the aqueous humor of human eyes under different oxygenation conditions. METHODS This prospective comparative interventional case series consisted of two parts. In the first part, 120 consecutive patients scheduled for cataract surgery were randomized into group I (control group) in which surgery was performed under local anesthesia inhaling 21% oxygen; gro...

Topical administration of prostaglandin F2a (PGF2a) produced a reduction in intraocular pressure in eyes of rabbits, cats, and cynomolgus monkeys. In rabbit eyes at 5 or 6 hr, 50 ng, 100 ng, or 250 ng of PGF2a caused a significant intraocular pressure reduction with a small miotic effect. Treatment with 500 ng, 750 fig, or 1000 ng of PGF2a lowered intraocular pressure significantly in cat eyes ...