OBJECTIVES The treatment of eating disorders is a complex process that relies not only on the use of psychotropic drugs but should include also nutritional counselling, psychotherapy and the treatment of the medical complications, where they are present. In this review recommendations for the pharmacological treatment of eating disorders (anorexia nervosa (AN), bulimia nervosa (BN), binge eatin...

γ-Aminobutyric acid (GABA), one of the main inhibitory neurotransmitters in the brain, interacts with three types of receptors for GABA GABAA, GABAB and GABAC. GABAA receptors, associated with binding sites for benzodiazepines and barbiturates in the form of a receptor complex, control opening of the chloride channel. When GABA binds to the receptor complex, the channel is opened and chloride a...

The negative side effects of classic antiepileptics, such as Valproate (VPA), often cause patients to discontinue their use. While the negative effects of VPA on lipid profile and thyroid functions have been well published, data regarding the side effects of new antiepileptics, such as levetiracetam (LEV), are not as conclusive. In this study, we investigated the effects of a well-known antiepi...

Background: Epilepsy is a common non-communicable disease that affects both young and the elderly, with cumulative lifetime incidence of 3%. Bone health may be impacted by prolonged AED use, study aims to investigate relationships between long-term antiepileptic usage, vitamin D levels, other outcomes. Methods: Comparative observational research was conducted on 60 children 30 healthy controls ...

This study reports the difficulties in the treatment and follow-up of patients with epilepsy and psychotic disorder and the orientation of neurologists about lifelong chronic effect of epilepsy towards psychiatric morbidity. Six patients (2 females, 4 males) complaining of generalized epilepsy, where the disease had started in the adulthood, for more than ten years, and suffered more than ten s...