phytochemical investigation of the aerial parts of euphorbia erythradenia bioss. (euphorbiaceae), one of iranian endemic euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using nmr and mass techniques. anti hiv...

This study was conducted to investigate the in vitro anti-inflammatory, anti-elastase, procollagen production, and astringent activities of <i>Euphorbia thymifolia</i> extracts prepared using two solvents for cosmetic application focusing on skin aging. Extraction performed by solvent extraction method with methanol (EM) hot-water (EW). Astringent activity EM increased concentration...

Zein-based nano/microparticles have been demonstrated to be promising carrier systems for both the food industry and biomedical applications. However, the fabrication of size-controlled zein particles has been a challenging issue. In this study, a modified anti-solvent precipitation method was developed, and the effects of various factors, such as mixing method, solvent/anti-solvent ratio, temp...

We developed solid dispersions, using the gas anti-solvent technique (GAS), to improve the oral bioavailability of the poorly water-soluble active component oridonin. The solubility of oridonin in supercritical carbon dioxide was measured under various pressures and temperatures. To prepare oridonin solid dispersions using the GAS technique, ethanol was used as the solvent, CO(2) was used as th...

Pharmacognosy Research,2021,13,4,246-256.DOI:10.5530/pres.13.4.18Published:October 2021Type:Original ArticleAuthors:Silva Waruni Randika, Nugara Ruwani Nilushi, Manage Pathmalal, Undugoda Lanka, Udayanga Dhanushka, Liyanage Renuka Nilmini, and Galhena Prasanna Author(s) affiliations:Silva Randika1,2, Nilushi1,*, Pathmalal2,3, Lanka1, Dhanushka1, Nilmini4, Prasanna5 1Department of Biosystems Tec...

in this study, the effect of recrystallization of naproxen in the presence of hydroxypropyl cellulose (hpc) on the release rate of drug was investigated. crystals were generated by the anti-solvent approach using the hpc solution in water as the anti-solvent. the samples were subjected to various physicochemical evaluations such as crystal size, scanning electron microscopy, fourier transform i...

Bauhinia variegata L (Synonyms: Phanera variegata Benth), commonly known as orchid tree or Kachnar belongs to the family of Leguminosae and found throughout India. All parts of the plants are used in the treatment of many ailments such as obesity, dyspepsia, bronchitis, leprosy, ulcer etc. The in-vitro antioxidant and anti-obesity properties of different solvent (hexane, chloroform, ethyl aceta...

An efficient synthesis of some novel coumarin derivatives via 1, 4- Michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (CSA) under solvent free conditions is described. The corresponding Michael addition products were obtained in good to excellent yield. The synthesized compounds were screened for their antibacterial activity against E. coli, S. aureus and an...

An efficient synthesis of some novel coumarin derivatives via 1, 4- Michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (CSA) under solvent free conditions is described. The corresponding Michael addition products were obtained in good to excellent yield. The synthesized compounds were screened for their antibacterial activity against E. coli, S. aureus and an...

Curcumin, the main yellow bioactive component of turmeric, has recently acquired attention by chemists due its wide range of potential biological applications as an antioxidant, an anti-inflammatory, and an anti-carcinogenic agent. This molecule fluoresces weakly and poorly soluble in water. In this detailed study of curcumin in thirteen different solvents, both the absorption and fluorescence ...