BACKGROUND Acute lung injury (ALI) induced by cardiopulmonary bypass (CPB, CPB-ALI) is a common and serious complication after cardiac surgery. And infants and young children are more prone to CPB-ALI. The purpose of this study was to investigate the perioperative changes of plasma gelsolin (pGSN) in patients below 3 years of age with cardiac surgeries and CPB, and determine whether pGSN are as...

Acute lung injury (ALI) remains a major cause of morbidity and mortality in critically ill patients. Despite improved understanding of the pathogenesis of ALI, supportive care with a lung protective strategy of mechanical ventilation remains the only treatment with a proven survival advantage. Most clinical trials in ALI have targeted mechanically ventilated patients. Past trials of pharmacolog...

Acute lung injury (ALI) is a critical illness syndrome with a mortality rate of 25-40%. Despite recent advances of our understanding of the pathophysiology of ALI, no pharmacologic therapies have been proven effective. The key pathogenesis of ALI is the activation of the coagulation cascade and impaired fibrinolysis, resulting in extensive fibrin and hyaline membrane deposition. Activated prote...

We solve the integral equation describing the propagation of light in an isothermal plane-parallel atmosphere of optical thickness τ∗, adopting a uniform thermalization parameter ǫ. The solution given by the ALI method, widely used in the field of stellar atmospheres modelling, is compared to the exact solution. Graphs are given that illustrate the accuracy of the ALI solution as a function of ...

We extend the notion of Gacs quantum algorithmic entropy, originally formulated for finitely many qubits, to infinite dimensional quantum spin chains and investigate the relation of this extension with two quantum dynamical entropies that have been proposed in recent years. Further, we prove an extension of Brudno’s theorem in quantum spin chains with shift dynamics. Acknowledgements I would li...

A study of 50 sugar maples {Acer saccharum) along Gates Mills Boulevard in Gates Mills, Ohio, showed that a tree's sap-sugar concentration tended to increase with decreasing tree health and increasing soil salt concentration. Relative tree health was determined by growth ring analysis. Salt concentration in soil was determined by measuring soil extract conductivity. Extract conductivity correla...

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The genetic basis of acute lung injury (ALI) is poorly understood. The myosin light chain kinase (MYLK) gene encodes the nonmuscle myosin light chain kinase isoform, a multifunctional protein involved in the inflammatory response (apoptosis, vascular permeability, leukocyte diapedesis). To examine MYLK as a novel candidate gene in sepsis-associated ALI, we sequenced exons, exon-intron boundarie...

The acute respiratory distress syndrome (ARDS)/acute lung injury (ALI) was described 30 yr ago, yet making a definitive diagnosis remains difficult. The identification of biomarkers obtained from peripheral blood could provide additional noninvasive means for diagnosis. To identify gene expression profiles that may be used to classify patients with ALI, 13 patients with ALI + sepsis and 20 pati...