Background Around 25% to 50% of lupus patients may present with alterations in the liver enzymes variable severity including fulminant hepatic failure. 1 Objectives To study prevalence, aetiology and outcome hospitalized enzyme abnormalities. Methods We analysed all from June 2018–June 2021. Patients abnormal enzymes(>2 times Upper Limit Normal) 2 were identified categorized as per standard ...

D-Vinylglycine (2-amino-3-butenoate) functions as a transamination substrate and irreversible inactivator of the homogeneous pyridoxal phosphate-dependent D-amino acid transaminases from Bacillus subtilis and Bacillus sphaericus. In the absence of alpha-ketoglutarate as co-substrate, vinyl-glycine causes little if any inactivation of either enzyme; in the presence of excess alpha-ketoglutarate,...

Diabetic male wistar rats (n=32) were fed diets supplemented with 1% bitter yam steroidal sapogenin extract or commercial diosgenin for three weeks. Thiobarbituric acid reactive substances (TBARS), conjugated dienes, lipid profile and the activities of alanine and aspartate transaminases and acid phosphatase were measured in the liver. Diabetic rats (groups B-D) lost weight significantly (p<0.0...

BACKGROUND/AIM A cryptogenic elevation of transaminases is the most common hepatic manifestation in celiac disease (CD). In adult patients and pediatric patients with cryptogenic hypertransaminasemia, the prevalence of CD was 4% and 12%, respectively. However, there are no related data from China in this regard. We aimed to investigate the status of CD in young Chinese patients with elevated tr...

We reviewed the literature regarding the serum levels of the enzymes aspartate aminotransferase, alanine aminotransferase, and gamma-glutamyl transferase in patients with chronic kidney disease on hemodialysis with and without viral hepatitis. Original articles published up to January 2013 on adult patients with chronic kidney disease on hemodialysis were selected. These articles contained the ...