A key goal in agent research is to be able to generate multimodal characters that can reflect a particular personality. The Big Five model of personality provides a framework for codifying personality variation. This paper reviews findings in the psychology literature to understand how the Big Five trait of emotional stability correlates with changes in verbal and nonverbal behavior. Agent beha...

The γ/σ1 and α/σ2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site. The clathrin adaptors AP-1 and AP-2 bind cargo proteins via two types of motifs: tyrosine-based Yxx␾ and dileucine-based [DE]XXXL[LI]. Although it is well established that Yxx␾ motifs bind to the ␮ subunits of AP-1 or AP-2, dileucine motifs have been reported to bind to either the ␮ or ␤ su...

Protein quality control (PQC) plays an important role in stemming neurodegenerative diseases and is essential for the growth of some cancers. Valosin-containing protein (VCP)/p97 plays a pivotal role in multiple PQC pathways by interacting with numerous adaptors that link VCP to specific PQC pathways and substrates and influence the post-translational modification state of substrates. However, ...

To study the response profile of the face-selective N170 component, an adaptation procedure was employed where adaptor and test stimuli were presented in rapid succession. Test stimuli came from 4 different face categories (upright, inverted, and eyeless faces and eyes-only images). The same face stimuli, as well as upright and inverted houses, served as adaptors. Strong N170 amplitude reductio...

Size adaptation describes the tendency of the visual system to adjust neural responsiveness of size representations after prolonged exposure to particular stimulations. A larger (or smaller) adaptor stimulus influences the perceived size of a similar test stimulus shown subsequently. Size adaptation may emerge on various processing levels. Functional representations of the adaptor to which the ...

Humans can identify individuals from their voice, suggesting the existence of a perceptual representation of voice identity. We used perceptual aftereffects--shifts in perceived stimulus quality after brief exposure to a repeated adaptor stimulus--to further investigate the representation of voice identity in two experiments. Healthy adult listeners were familiarized with several voices until t...

The social context in which an action is embedded provides important information for the interpretation of an action. Is this social context integrated during the visual recognition of an action? We used a behavioural visual adaptation paradigm to address this question and measured participants' perceptual bias of a test action after they were adapted to one of two adaptors (adaptation after-ef...

Population genomic studies have increased in the last decade, showing great potential to understand evolutionary patterns a variety of organisms, mostly relying on RAD sequencing techniques obtain reduced representations genomes. Among them, 2b-RAD can provide further secondary reduction adjust experimental costs by using base-selective adaptors, although its impact genotyping is unknown. Here ...

A common feature of hematopoietic activating immunoreceptors resides in their association at the cell surface with transmembrane signaling adaptors. Several adaptors, such as the CD3 molecules, FcRgamma and KARAP/DAP12, harbor intracytoplasmic immunoreceptor tyrosine-based activation motifs (ITAM) that activate Syk-family protein tyrosine kinases. In contrast, another transmembrane adaptor, DAP...

We previously demonstrated, using fluorescence recovery after photobleaching, that clathrin in clathrin-coated pits at the plasma membrane exchanges with free clathrin in the cytosol, suggesting that clathrin-coated pits are dynamic structures. We now investigated whether clathrin at the trans-Golgi network as well as the clathrin adaptors AP2 and AP1 in clathrin-coated pits at the plasma membr...