Atopic dermatitis (AD) is the extremely complicated syndrome that various abnormalities develop in a heap. There are various factors in patients for the onset and exacerbation of AD, including genetic cofactors of individuals, environmental factors, the failure of the skin barrier function, unfavorable regulation of the immune system, and the hypersensitivity of sensory nerves. In recent years,...

A learner who can solve a problem cannot always understand the problem adequately. In order to deeply understand a problem, it is necessary that he/she poses various problems which can be solved by the “solution method” of the problem. Moreover, after he/she poses problems, it is necessary that he/she considers and indicates differences between the problems posed by him/her, too. So, we develop...

Spanning 30 years and 40 individual videogames across a range of platforms, Pac-Man is one of the most recognizable of all videogame characters and a pop–culture icon. In spite of its widespread popularity, the game receives little sustained academic engagement or analysis. In an attempt to address this, the paper argues that in its classic iterations PacMan generates complex notions of space a...

Paralinguistics organizers such as parenthesis, footnotes, and pop-up fields on screen, should play an important role signalling the writer’s “minimization” intention when secondary points are concerned. This experiment investigated the role of pop-up fields compared to brackets in an information retrieval task. The results showed that, in this kind of task, putting secondary pieces of informat...

Neuropsychological studies show that cognitive deficits associated with Alzheimer's disease (AD) are distinct from age-associated cognitive decline. Quantitative and qualitative differences are apparent across many cognitive domains, but are especially obvious in episodic memory (particularly delayed recall), semantic knowledge, and some aspects of executive functions. The qualitatively distinc...

Down Syndrome (DS) patients develop characteristic Alzheimer's Disease (AD) neuropathology after their middle age. Prominent neuronal loss has been observed in the cortical regions of AD brains. However, the underlying mechanism leading to this neuronal loss in both DS and AD remains to be elucidated. Calcium overloading and oxidative stress have been implicated in AD pathogenesis. Two major is...

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a severe derangement of cognitive functions, primarily memory, in elderly subjects. As far as the functional impairment is concerned, growing evidence supports the "disconnection syndrome" hypothesis. Recent investigations using fMRI have revealed a generalized alteration of resting state networks (RSNs) in patients affec...

Atopic dermatitis (AD) together with asthma and allergic rhinitis represents the most typical manifestation of “atopic constitution”. AD was known since ancient times and also Job was probably affected by it. In the Bible (Book of Job) we read:” So went Satan forth from the presence of the Lord and smote Job with sore boils from the sole of his foot unto his crown; and he took him a potsherd to...

Mesothoracic wings have been examined and compared in 32 species representing 20 genera of Afrotropical Scutelleridae. Morphological characters of the corium are described. Three main types of mesothoracic wing venation patterns can be recognized. The taxonomic significance of forewing characters in Scutelleridae is briefly discussed.