نتایج جستجو برای: acetylneuraminic acid

تعداد نتایج: 747460  

Journal: :Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie 1986
S Scharpé M van Sande D Hendriks Y Kasahara

Angiotensin converting enzyme (dipeptidyl carboxypeptidase, kininase II; EC 3.4.15.1), is a membrane bound glycoprotein, playing an important role in the renin-aldosterone system. The enzyme contains a carbohydrate moiety, consisting of fucose, mannose, galactose, N-acetylglucosamine and N-acetylneuraminic acid. Treatment with neuraminidase (EC 3.2.1.18) removes sialic acid from the molecule. T...

Journal: :Biochimie 2001
A Varki

Classic studies suggested that the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc) is an oncofetal antigen in humans, being immunogenic in adult humans and yet apparently expressed in human fetuses and tumors. We and others have recently found that the human deficiency of Neu5Gc can be explained by an inactivating mutation in the gene encoding CMP-N-acetylneuraminic acid hydroxy...

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