نتایج جستجو برای: 212
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Since their discovery, miRNAs have emerged as a promising therapeutical approach in the treatment of several diseases, as demonstrated by miR-212 and its relation to addiction. Here we prove that the miR-212/132 cluster can be regulated by morphine, through the activation of mu opioid receptor (Oprm1). The molecular pathways triggered after morphine administration also induce changes in the lev...
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MicroRNAs (miRNAs), a group of small non-coding RNAs that fine tune translation of multiple target mRNAs, are emerging as key regulators in cardiovascular development and disease. MiRNAs are involved in cardiac hypertrophy, heart failure and remodeling following cardiac infarction; however, miRNAs involved in hypertension have not been thoroughly investigated. We have recently reported that spe...
Carl Procko, Yun Lu, and Shai Shaham* Laboratory of Developmental Genetics The Rockefeller University 1230 York Avenue New York, NY 10065 USA *To whom correspondence should be addressed: Tel: (212) 327-7126, Fax: (212) 3277129, email: [email protected] Running title: Genetic control of sensory organ remodeling in C. elegans Genetics: Published Articles Ahead of Print, published on January ...
This case study discusses briefly the economic and legal issues pertaining to the antitrust case of the United States and a number of States against Microsoft. * Stern School of Business, New York University, New York, NY 10012, (212) 9980864, fax (212) 995-4218, http://www.stern.nyu.edu/networks/, [email protected] Copyright ©, N. Economides
The synthetic peptides p195-212 and p259-271, representing amino acids 195-212 and 259-271 of the alpha subunit of the human acetylcholine receptor, preferentially stimulate T cells of patients with myasthenia gravis and are immunodominant T-cell epitopes in SJL and BALB/c mice, respectively. We designed and synthesized analogs of these peptides that contain single amino acid substitutions. An ...
PURPOSE The 21-gene (Oncotype DX) recurrence score (RS) assay is useful in predicting the benefits of adjuvant chemotherapy for early breast cancer patients and is widely used in Western countries. However, to date, it has not gained much popularity in East Asia. We analyzed the results from five institutions' experience from using the 21-gene assay and examined the impact of assay results on d...
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