Thyrotropin-releasing hormone (TRH) is engaged in the modulation of the hypothalamo-neurohypophysial system activity. Effects of repeated intravenously injections of TRH in a dose of 100 ng/100 g b.w. on vasopressin (VP) and oxytocin (OT) biosynthesis and release from the hypothalamo-neurohypophysial system was investigated in rats in different age (1-, 3- or 7-months of the life). To estimate ...

The objective of this study was to determine the effect of increased vitamin D fortification (250 IU/serving) of high-temperature, short-time (HTST)-processed 2% fat milk, UHT-processed 2% fat chocolate milk, and low-fat strawberry yogurt on the sensory characteristics and stability of vitamin D during processing and storage. Three replicates of HTST pasteurized 2% fat milk, UHT pasteurized 2% ...

The present controlled-training double-blind study (supplemented (S) group, n 7; placebo (P) group, n 10) was designed to investigate whether an antioxidant mixture (Se 150 microg, retinyl acetate mg, ascorbic acid 120 mg, alpha-tocopheryl succinate 20 mg) would allow overloaded triathletes to avoid adaptation failure in the antioxidant system [corrected]. Dietary intakes were recorded. The sup...

Background: Olfactory dysfunction (OD) is a common neurosensory manifestation in long COVID. An effective and safe treatment against COVID-19-related OD needed. Methods: This pilot trial recruited COVID patients with persistent OD. Participants were randomly assigned to receive short-course (14 days) oral vitamin A (VitA; 25,000 IU per day) aerosolised diffuser olfactory training (OT) thrice da...

BACKGROUND Complement activation during reperfusion of ischemic myocardium augments myocardial injury, and complement inhibition with C1-esterase inhibitor (C1-INH) at the time of reperfusion exerts marked cardioprotective effects in experimental studies. Application of C1-INH in newborns, however, was recently reported to have dangerous and even lethal side effects. This study addresses the es...

The aim of this study was to determine: (a) whether progesterone affects the expression of the gene for its own receptor, thereby affecting its own synthesis; (b) whether oxytocin (OT) and noradrenaline (NA) influence the expression of gene for receptor (R) of OT (OT-R), progesterone (PR-R), and β2-R, determined by means of real-time PCR; (c) whether OT, progesterone, and NA affects the protein...

Genetic predisposition and environmental conditions are mentioned among the factors modifying the synthesis of IgE immunoglobulin. The aim of the study was to analyze chosen factors in children with high total concentration of IgE (>100 IU/ml). The study included 261 children who were divided according to the serum level of IgE into 3 groups: I IgE 101-1000 IU/ml; II IgE >1001 IU/ml and III (co...

  Objective(s): The effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study.   Materials and Methods: Male Wistar rats were randomly divided into control sedentary (C), moderate trained (MT), (V=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (OT) (V=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrai...