AIMS AND BACKGROUND Endometrial carcinoma is a rare cause of brain metastases, accounting for less than 1% of all metastatic lesions to the brain. This report aims to review our experience in the treatment of patients with brain metastases from endometrial carcinoma in order to establish the characteristics of these patients and evaluate the results and efficacy of whole-brain radiation therapy...

BACKGROUND Patients with brain metastases from lung cancer have poor prognoses and short survival time, and they are often excluded from clinical trials. Whole-cranial irradiation is considered to be the standard treatment, but its efficacy is not satisfactory. The purpose of this phase II clinical trial was to evaluate the preliminary efficacy and safety of the treatment of whole-brain irradia...

OBJECTIVES Hippocampal avoidance during whole-brain radiotherapy is performed to prevent neural stem cell injury causing neurocognitive dysfunction. Nevertheless, the estimated risk of metastases in hippocampal avoidance area in small-cell lung cancer is unknown. The current study aimed to characterize the metastatic distribution within the brain relative to the hippocampus, estimate the incide...

Lung cancer is the most frequent oncological disorder and has been main topic in congresses. There have countless changes diagnosis treatment, improvements diagnostic methods, more effective less invasive curative care systemic treatments (new drugs molecular targets). In whole therapeutic spectrum, radiotherapy plays a significant role at brain metastasis level are very relevant. Brain metasta...