Tobacco seed cake is a by-product with interesting characteristics for animal nutrition, due to its high protein content. The focus of this study is to evaluate if tobacco seed cake, administered in feed, can affect principal serum metabolic parameters of weaned piglets in order to establish if it can be used as both a delivery system of edible vaccines and an alternative protein source in pigl...

OBJECTIVE Boluses are used in high-energy radiotherapy in order to overcome the skin sparing effect. In practice though, commonly used flat boluses fail to make a perfect contact with the irregular surface of the patient's skin, resulting in air gaps. Hence, we fabricated a customized bolus using a 3-dimensional (3D) printer and evaluated its feasibility for radiotherapy. METHODS We designed ...

Purpose : To study the safety of 99m Tc-1-Thio-D-Glucose ( Tc-TG) using, as well its pharmacokinetics and dosimetric characteristics. Material methods The 99mTc-TG was studied in 12 patients with lymphomas. performed after a bolus injection 729 ± 102 MBq Tc-TG. Whole body anterior posterior planar imaging at 2, 4, 6, 24 hours post-injection. In addition, all underwent SPECT/CT scanning 2 only S...

It is of interest to discern the energy-dependence of American Association of Physicists in Medicine (AAPM) TG-43 brachytherapy dosimetry parameters. Using Monte Carlo calculation geometry and techniques (MCNP), dependence of these parameters was calculated as a function of photon energy, in general, and for the MED3633 103Pd source using a discretized approach. Results were weighted and summed...

PURPOSE To present experimental dosimetry results for the new IsoSeed I25.S17plus (125)I brachytherapy source, in fulfillment of the American Association of Physicists in Medicine recommendation for, at least one, experimental dosimetry characterization of new low-energy seeds before their clinical implementation. METHODS AND MATERIALS A batch of 100 LiF thermoluminescent dosimeter (TLD)-100 ...

BACKGROUND Since the term chronic allograft nephropathy (CAN) was removed from the Banff scheme in 2005, transplant glomerulopathy (TG) has been regarded as a clinicopathological entity that is one of the major causes of graft loss. To assess the distinction between CAN and TG, we performed a comprehensive evaluation comparing TG with traditional CAN. METHODS We compared the clinicopathologic...

This study presents the results of EGSnrc Monte Carlo calculations of the dose distribution surrounding a high dose rate Yb brachytherapy source and 14 high dose rate and pulsed dose rate Ir brachytherapy sources. Energy-weighted spectra of emitted photons, a full set of TG-43 dosimetry parameters, along-away dose tables, and a description of the materials and geometry used for each source are ...

AIM To evolve a fast dose verification method for high-dose-rate (HDR) brachytherapy treatment plans and to demonstrate its applicability in different clinical cases. MATERIALS AND METHODS We developed a software tool in VC++ for the Varisource HDR unit for HDR dosimetry plan verification using TG-43 parameters. HDR treatment dosimetry of a number clinical cases using Varisource was verified ...

AIM To evaluate the possible role of dosimetric parameters according Normal Tissue Complication Probability (NTCP) model as predictive of late toxicity and cosmesis in hypofractionated whole-breast three-dimensional conformal radiotherapy. PATIENTS AND METHODS A retrospective analysis on 215 consecutive early breast cancer patients treated with breast conserving surgery and adjuvant hypofract...

Frontotemporal dementia (FTD) causes progressive personality, behavior and/or language disturbances and represents the second most common form of dementia under the age of 65. Over half of all FTD cases are classified pathologically as frontotemporal lobar degeneration (FTLD) with TAR DNA-binding protein of 43 kDa (TDP-43) pathology (FTLD-TDP). In FTLD-TDP brains, TDP-43 is phosphorylated, C-te...