Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system. Although testicular cancer can be derived from any cell type found in the testicles, more than 95% of testicular cancers are germ cell tumors. Most of the remaining 5% are sex cord-gonadal stromal tumors derived from Leydig cells or Sertoli cells. Over man's lifetime, his risk of testicular cance...

Neuroblastoma (NB) is the most common type of extracranial solid tumor in children with a high prevalence in toddlers. For childhood cancer survivors, preservation of reproductive potential is an important factor for quality of life. The optimization of NB minimal residual disease (MRD) detection in testicular tissue is crucial to evaluate the risk of malignant cell reintroduction. The first st...

An 8-year-old intact rabbit was presented to a veterinary hospital with a complaint of enlarged left scrotum. Histological examination revealed a single large cyst adjacent to an efferent ductule-like tissue. The cyst wall was composed of monolayer cuboidal cells surrounded by dysplastic testicular tissue, and the seminiferous tubules were not developed at all. The epithelial cells of the cyst ...

Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system. Although testicular cancer can be derived from any cell type found in the testicles, more than 95% of testicular cancers are germ cell tumors. Most of the remaining 5% are sex cord-gonadal stromal tumors derived from Leydig cells or Sertoli cells. Over man's lifetime, his risk of testicular cance...

Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system. Although testicular cancer can be derived from any cell type found in the testicles, more than 95% of testicular cancers are germ cell tumors. Most of the remaining 5% are sex cord-gonadal stromal tumors derived from Leydig cells or Sertoli cells. Over man's lifetime, his risk of testicular cance...

Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system. Although testicular cancer can be derived from any cell type found in the testicles, more than 95% of testicular cancers are germ cell tumors. Most of the remaining 5% are sex cord-gonadal stromal tumors derived from Leydig cells or Sertoli cells. Over man's lifetime, his risk of testicular cance...

OBJECTIVE [corrected] To report a rare case of secondary testicular plasmocytoma in the context of a testicular mass. METHOD We introduced a patient with plasmocytoma and a testicular infiltration of his systemic affection. RESULT An inguinal orquiectomy was performed to treat the testicular infiltration and no recurrence of the process was seen after 6 months of follow up. CONCLUSIONS Pl...

BACKGROUND Long term alcohol use has been implicated in men with sexual disorders including suppression of testosterone levels as well as testicular morphological changes. OBJECTIVE This research investigated the ability of Telfairia occidentalis (T.O.) to attenuate the damaging effects of alcohol on the testicular parameters. MATERIALS AND METHODS Thirty male Sprague-Dawley rats, 170-190 g...

Fluoxetine is a selective serotonin reuptake inhibitor is commonly prescribed to treat maternal depression in pregnancy and lactation. This study aimed to investigate the effects of maternal exposure to fluoxetine via lactation on testicular tissue, sperm parameters including count, motility, viability, and normal morphology and testicular oxidative stress status in male mice offspring. Ten mic...

Serum testosterone concentrations are reduced in men with rheumatoid arthritis and in rats with adjuvant-induced arthritis, a common model for rheumatoid arthritis. To understand the mechanism responsible for this reduction, testosterone production by testicular cells and Percoll-purified Leydig cells from nonarthritic and arthritic rats was studied. Leydig cells in crude interstitial cell prep...