In the present study, Fe3O4 super paramagnetic nanoparticles were synthesized via co-precipitation of Fe3+ and Fe2+ chloride salts in the presence of ammonia Solution. The product was characterized by Fourier Transform Infrared spectroscopy (FT-IR), Transmission Electron Microscopy (TEM), and zeta–potential particle size distributing methods. The synt...

The most recent data on mechanisms of spin trapping of nitric oxide (NO) by iron dithiocarbamate complexes in animal and plant cells and tissues are considered. The rationale is as follows: 1 In the absence of NO in cells and tissues, iron binds primarily to compounds others than dithiocarbamate ligands, e.g., tricarbonic acids. 2. Predominant binding of iron to dithiocarbamate ligands takes pl...

Magnetic particle imaging (MPI) is a new medical imaging approach that is based on the nonlinear magnetization response of super-paramagnetic iron oxide nanoparticles (SPIOs) injected into the blood stream. To date, real-time MPI of the bolus passage of an approved MRI SPIO contrast agent injected into the tail vein of living mice has been demonstrated. However, nanoparticles are rapidly remove...

BACKGROUND Advances of nanotechnology have led to the development of nano-materials with both potential diagnostic and therapeutic applications. Among them, Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) have received particular attention. Modified EDC coupling fraction was used to fabricate the SPION-C595 as an MR imaging contrast agent for breast cancer detection in early stages. METH...

Introduction: Ultra-small Super-Paramagnetic Iron Oxide (USPIO) is commonly used as an MRI labeling agent to track cell migration. Different methods exist for USPIO detection, including gradient-based methods (1), and RF-based methods (2,3). Among the latter, IRON relies on suppression of on-resonant spins using a conventional water saturation pre-pulse, and results in positive contrast in a bl...

Despite the large efforts to prepare super paramagnetic iron oxide nanoparticles (MNPs) for biomedical applications, the number of FDA or EMA approved formulations is few. It is not known commonly that the approved formulations in many instances have already been withdrawn or discontinued by the producers; at present, hardly any approved formulations are produced and marketed. Literature survey...

Using magnetic nanoparticles to absorb alternating magnetic field energy as a method of generating localized hyperthermia has been shown to be a potential cancer treatment. This report demonstrates a system that uses tumor homing cells to actively carry iron/iron oxide nanoparticles into tumor tissue for alternating magnetic field treatment. Paramagnetic iron/ iron oxide nanoparticles were synt...

A new kind of magnetic induction heating materials-carbon coated iron nanoparticles(CCINS) was prepared by arc method and they were used for cancer therapy. The measurement of nanomaterials revealed that they are super-paramagnetic and exhibit a very strong induction heating ability.The magnetic induction heating property was measured by the conduction by Bio-heat method. Heating effect of pig ...