Natural products provide excellent potential leads for drug development because of their chemical diversity and biological functionality. However, the productivity of discovery of new, pharmacologically active natural products has traditionally been low due to inherent difficulties and costs associated with extract dereplication, i.e., isolation, purification and structure elucidation of indivi...

Background: There are varieties of purification techniques for separation of human plasma proteins such as salting out, ion exchange chromatography, and ethanol fractionation. There are limitations for each method, for example in salting out method, the salt has to be removed in an additional step. Ion exchange chromatography is difficult for scaling up, and plasma fractionation is a time consu...

Different numerical and analytical models are presently available that provide the tools to predict pollutant and water transfer processes between the soil surface and the groundwater level. Among the existing models, the Hydrus-1D model has been used for years in the prediction of water and pollutants transfer in the unsaturated zone. The main purpose of this paper was to model the movement of...

background: the presence of lead in natural waters has become an important issue around the world. lead has been identified as a highly toxic metal that can cause severe environmental and public health problems and its decontamination is of utmost importance. the aim of this work was to evaluate the adsorption of lead (pb(ii)) on waste tea leaves as a cheap purification method. methods: in this...

gorganrood river is one of the three main rivers in golestan province have a basic role in golestan water supply. to study gorganrood water quality and estimating maximum allowable pollutant, water quality data was used from 8 stations. purification of this river has been studied by two methods: statistical and experimental methods. each method showed that the gorganrood river at present condit...

One of the most appropriate methods for elimination of trace impurities in helium is cryogenic adsorption process. So, in this study design and construction of cryogenic adsorption helium purification system (3 Nm3.hr-1, 80 bar) carried out using activated carbon as adsorbent at 77K. To evaluation of adsorption dynamics and effect of pressure on elimination of trace impurities, helium purificat...

In this study, anion-exchange chromatography was used to purify factor VII and factor IX from prothrombin complex (PPSB), which contains coagulation factors II, VII, IX and X. For this purpose, DEAE-Sepharose CL-6B gel , Pharmacia column XK-26 , high flow rate and two stepwise gradients with phosphate citrate buffer were used. The yield of the two lyophylized products, factor VII and factor...

Egg-laying hens were immunized with the Echis carinatus venom and the resulting antibodies were extracted from egg yolk by four different purification methods. The chicken egg yolk antibodies were purified by the water dilution method, polyethylene glycol (PEG) and ammonium sulphate precipitation method, chloroform extraction and the Lithium sulphate precipitation method. These methods were com...