background: type-i diabetes is an autoimmune inflammatory disease in which pancreatic ß-cells are selectively destroyed by infiltrating cells. tnf-related apoptosis-inducing ligand (trail) is a type-ii membrane protein of the tnf superfamily which is expressed in different tissues, including pancreas and lymphocytes. in humans, trail interacts with four membrane receptors. trail-r1 and trail-r2...

Background: Type-I diabetes is an autoimmune inflammatory disease in which pancreatic ß-cells are selectively destroyed by infiltrating cells. TNF-related apoptosis-inducing ligand (TRAIL) is a type-II membrane protein of the TNF superfamily which is expressed in different tissues, including pancreas and lymphocytes. In humans, TRAIL interacts with four membrane receptors. TRAIL-R1 and TRAIL-R2...

In this paper, the effect of wind load on port portal crane is simulated by experimental method, and anti-wind anti-skid performance tested. This experiment an important method to study action mode force skid resistance crane, provides basis for evaluation wind-proof safety crane.

Molecular farming has been considered as a secure and economical approach for production of biopharmaceuticals. Human TNF Related Apoptosis Inducing Ligand (TRAIL) as a promising biopharmaceutical candidate has been produced in different expression hosts. However, little attention has been paid to molecular farming of the TRAIL in spite of numerous advantages of plant expression systems. Theref...

assessment and management of the environmental impacts of forest harvesting operations have become increasingly critical factors in practicing commercial forestry. this study investigated soil disturbance from a forest logging system operation on an 8-hectare mixed broadleaved stand in compartment no. 309 in gorazbon district in kheyrud educational and research forest. the objective of this stu...

Molecular farming has been considered as a secure and economical approach for production of biopharmaceuticals. Human TNF Related Apoptosis Inducing Ligand (TRAIL) as a promising biopharmaceutical candidate has been produced in different expression hosts. However, little attention has been paid to molecular farming of the TRAIL in spite of numerous advantages of plant expression systems. Theref...

This paper presents results of a research aiming at modeling the evolution of road surface skid resistance using statistical and phenomenological approaches. Data are provided by a database composed of measurements collected on French roads during ten years: skid resistance values (Sideway Force Coefficient measured by SCRIM machine), macrotexture values (Mean Profile Depth), road geometry, tra...

It is important to minimize the energy consumption of autonomous ground vehicles (AGVs) deployed in real world missions. One of the ways that this can be accomplished is to choose the vehicle’s motion to minimize the mechanical and electrical energy usage required by the vehicle’s motion. This paper considers energy efficient motion planning for skid-steered AGVs, an important and large class o...

Objective(s): Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis in tumor cells, more than half of tumors including non-small cell lung cancer (NSCLC) exhibit TRAIL-resistance. The purpose of this study was to determine whether subtoxic-dose cisplatin and TRAIL could synergistically enhance apoptosis on NSCLC cells and investigate its under...