Evidence has been offered that influenza virus which has been heated at 56 degrees C. for 30 or more minutes loses some of its capacity to agglutinate red cells and may completely lose its power to elute from cells on which it has been adsorbed. Such heat-inactivated virus does not possess the capacity to destroy the virus inhibitor in normal rabbit serum and this appears to be the explanation ...

BACKGROUND The group-specific component protein-derived macrophage-activating factor (GcMAF) has various biological activities, such as macrophage activation and antitumor activity. Clinical trials of GcMAF have been carried out for metastatic breast cancer, prostate cancer, and metastatic colorectal cancer. In this study, despite the complicated purification process of GcMAF, we used enzymatic...

In 1942 Taylor, Race, Prior, and Ikin reported an anti-Rh serum which failed to agglutinate Rhpositive cells in saline suspension except when diluted. They thought that this prozone was due to antigen and antibody not being present in optimal proportions, and that the mechanism was similar to that of the zones that occur in precipitation reactions. Wiener (1944) described incomplete Rh antibodi...

In 1942 Taylor, Race, Prior, and Ikin reported an anti-Rh serum which failed to agglutinate Rhpositive cells in saline suspension except when diluted. They thought that this prozone was due to antigen and antibody not being present in optimal proportions, and that the mechanism was similar to that of the zones that occur in precipitation reactions. Wiener (1944) described incomplete Rh antibodi...

magnesium (mg) deficiency has not usually been considered in clinical practice due to lack of relevant blood tests and because the symptoms are often vague and nonspecific. serum concentrations may not adequately reflect mg status. mg loading test (mlt) can provide infonnation on total body mg stores. we prospectively studied 21 critically ill patients (10 male, 11 female) admitted to the icu, ...

the present study aimed to assess changes in resting and maximum heart rates as primary indicators of cardiac autonomic function in metabolic syndrome (mets) patients and to determine their value for discriminating mets from non-mets. 468 participants were enrolled in this cross-sectional study and assessed according to the updated adult treatment panel iii (atp-iii) definition of mets. resting...

BACKGROUND AND OBJECTIVES Rituximab reacts specifically with the CD20 antigen and induces B-cell depletion. This could interfere with the production of autoantibodies in some immune diseases. The objective of this study was to assess the effects of rituximab in autoimmune hemolytic anemia and thrombocytopenia. DESIGN AND METHODS Seven patients (one with cold agglutinin disease, two with warm ...

Structural studies of oligosaccharide chains of immunoglobulin G (IgG) in serum have revealed a specific galactosylation deficiency associated with rheumatoid arthritis (RA). Using a two-site lectin-immunofluorometric assay, I studied the interaction of IgG with immobilized lectins. Compared with control IgG, IgG purified from RA patients' sera bound up to 40-fold more strongly to immobilized B...

E. P. Pick’ in rgor associated a number of antisubstances individually with the one or the other of the two serum globulin fractions of the Hofmeister classification. In the pseudoglobulin (3.4 to 4.6 saturated ammonium sulphate solution)2 group of antibodies he placed the diphtheria and tetanus antitoxins and the typhoid agglutinin of horse serum; the lower or euglobulin fraction (2 .g to 3.4 ...

Seven types of ferritinized lectin were used to examine the distribution of glycoconjugates on the outer segment membranes of lamprey photoreceptor cells. Ultrastructural pre-embedding labeling revealed that peanut agglutinin, soybean agglutinin and Ricinus communis agglutinin I were preferentially bound to the proximal, lateral and luminal surfaces of the long cell outer segments, whereas Grif...