Rheumatoid arthritis is one of the most common debilitating rheumatological disorders. A subcutaneous rheumatoid nodule usually occurs in advanced cases of rheumatoid arthritis and is also a hallmark of the chronicity of the disease. They are also the most common extra-articular manifestation of rheumatoid arthritis. We present a case of a giant rheumatoid nodule, developed on the left elbow.

Rheumatoid arthritis is a crippling disease that is often associated with severe pain, suffering, and diminished function, thereby detracting from an optimal quality of life. Over the past decade a greater appreciation of the pathophysiology of rheumatoid arthritis has been gained. In the past "decade of pain research," biologic agents which may modify rheumatoid arthritis have emerged as poten...

OBJECTIVES To report benign rheumatoid nodules in a woman with chronic lymphocytic leukaemia and borderline lepromatous leprosy and to summarise the features of the patients with adult onset benign rheumatoid nodules. METHODS A 66 year old woman with chronic lymphocytic leukaemia and borderline lepromatous leprosy who presented with subcutaneous elbow nodules, which were at first suspected to...

One hundred fifty two patients with Juve­ nile rheumatoid arthritis were retrospectively studied in an effort to determine the efficacy of synovectomy in thi's disease.  Twenty-five of 117 closely observed patients underwent synovectomy following failure to be controlled by more conservative measures. Analysis of the end-results on the basis of age, sex, stage of disease, and individual joints...

purpose: to report bilateral terrien’s marginal degeneration, circumferential peripheral corneal ectasia and posterior polymorphous dystrophy in a patient with rheumatoid arthritis. case report: a 24-year-old male patient, who was known case of rheumatoid arthritis from 8 years before, presented with decreased vision since four years ago. comprehensive ophthalmic eye exami-nation revealed bilat...

rheumatoid arthritis is the most common inflammatory joint disease with 1 percent prevalence in community which presents with symmetrical polyarthritis of hands with inflammatory behavior. several studies in recent years were conducted for evaluation of inflammatory cytokines such as il1-α (interlukin 1α) and tnf- α (tumor necrosis factor) in rheumatologic disorders including rheumatoid arthrit...

background and aim: autoimmune inner ear disease (aied) may accompany certain systemic conditions, such as rheumatoid arth­ritis, and manifest audiovestibular dysfunction. this study aimed to compare the vestibular function between rheumatoid arthritis (ra) patients and normal subjects using cervical vestibular-evoked myogenic potentials and caloric tests. methods: in this cross-sectional study...

OBJECTIVES Rheumatoid arthritis is a polygenically controlled systemic autoimmune disease. Rheumatoid vasculitis is an important extra-articular phenotype of rheumatoid arthritis that can result in deep cutaneous ulcers. The objective of this study was to establish a correlation between the frequency of major histocompatibility complex class I/II alleles and killer immunoglobulin-like receptor ...

Much has been written about the'controversial subject of respiratory system involvement in rheumatoid arthritis since the paper of Eliman and Ball (1948). It is now generally accepted that certain respiratory conditions, although more or less uncommon, are true manifestations of rheumatoid disease. These are rheumatoid nodules occurring in pleura and lungs (Robertson and Brinkman, 1961) and nod...

In analogy with the two categories of reactants which are used in the serological tests for the unusual category of macroglobulins called rheumatoid factor, two fluorescent reactants have been prepared for the detection of rheumatoid factor in situ in tissue sections: fluorescent antigen-rabbit antibody (immune) complex, in the present study, and fluorescent aggregated human gamma-globulin, in ...