For evaluation the stability and potency of anthrax vaccine prepared in Razi Vaccine and Serum Research Institute in Iran, samples of different batches of vaccine were kept at 4-8 °C (refrigerator), 20-25 °C (room temperature) and 37 °C (incubator).The viable spores/ml of vaccines were determined using plate–counting method before and after holding at different temperatures monthly. Vaccine p...

context tuberculosis (tb) disease caused by mycobacterium tuberculosis (mtb) remains as one of the leading infectious causes of death and disease throughout the world. the history of tuberculosis as a worldwide fatal illness traces back to antiquity, being a well-known disease in ancient civilizations. evidence acquisition presented here, is a brief review of the history of tuberculosis and bac...

colon transit time study with radio opaque markers is a simple method for assessment of colon motility disorder in patients with chronic idiopathic constipation. appendicitis caused by metallic objects has been reported repeatedly and is very important because of its complications. we report a case of acute appendicitis that was induced by impaction of radio opaque markers after colon transit t...

An inactivated trivalent fowl cholera vaccine consisted of serotypes 1, 3 and 4 Pasteurella multocida strains was prepared. The vaccine provided 70-100% protection against challenge with homologous starins. ELISA assay showed a considerable increase in antibody titer after towice vaccination of 8 weeks chickens. It was found that the trivalent vaccine can induce immunogenic response in vaccinat...

Background: Due to high genetic variation in human leukocyte antigen )HLA( alleles, epitope-based vaccines don’t show equal efficacy in different human populations. therefore, we proposed a multi-epitope vaccine against SARS-CoV-2 for Iranian populations. Materials and Methods: For this purpose, the proteins without allergenicity and high antigenicity as well as conservancy level from SARS-CoV...

Frequent vaccination failures have occurred in the broiler farms in Eurasian countries during Newcastle disease outbreaks. The disease is enzootic in many countries of the region, especially in southwest Asia. I-2 vaccine has been used successfully in village chickens in many Asian and African countries. Our preliminary study showed good efficacy of the vaccine in broiler chickens. Therefore th...

Background and Aims: Influenza vaccination is one of the best way to prevent and control influenza worldwide. It is manufactured by WHO-licensed companies based on the WHO expertise committee annually. The aim of this study was partial quality control of the commercial human influenza vaccine 2008-9 and its matching with the circulating strains. Materials and Methods: The trivalent imported vac...

background: hepatitis b virus (hbv) fails to produce appropriate immune responses in some healthy individuals; thus, different strategies have been adopted to promote immune responses. the current study aimed at evaluating the efficacy of hbv vaccine coadministered with tetanus-diphtheria (td) vaccine compared with hbv vaccine in healthy individuals through measuring hepatitis b surface antibod...

background: hepatitis b virus (hbv) infection is an endemic infection in nigeria. health care workers (hcws) are at risk of occupational exposures to hbv-infected blood and body fluids. objective: to determine the prevalence and determinants of hbv vaccine coverage among hcws in two teaching hospitals in nigeria. methods: this cross-sectional study was undertaken in 2011 and 2012 in two teachin...