electronic effects were investigated on the singlet–triplet energy gaps of divalent unsaturated seven- membered ring r2c6h6m (m=c, si, ge, sn, pb, r= –h, -ch3, i-pr , t-bu) at b3lyp/6-311++g** level. all the triplet states of r2c6h6c were more stable than the related the singlet states while all the singlet states of r2c6h6m (m= si, ge, sn, pb, r= –h, -ch3, i-pr , t-bu) were more stable than th...

several modalities of drug administration have been investigated to improve bioavailability and to reduce 5-fu related toxicity. the aim of present study was to evaluate the effect of skimmed milk on the absorption and metabolism of 5-fu in rabbits, mice and dogs. it was further aimed to determine its route related toxicity in rabbits.    plasma concentration of both 5-fu and its metabolite 5-f...

background: survival of colorectal cancer (crc) patients is considerably stage-dependent therefore, early diagnosis is a pivotal factor in decreasing mortality and morbidity associated with this cancer. gm-csf and il-7 are reported to increase in different cancers and we aim to investigate the pre-treatment serum levels of gm-csf and il-7 in iranian patients with colorectal cancer. methods: 127...

background: hydrogen peroxide (h2o2), produced by gamma ray irradiation to watery solution, was used as an analytical parameter for dosimetry of cobalt-60 (60co) radiation. materials and methods: detection of the produced h2o2 was carried out using two methods: an amperometric biosensor fabricated by immobilization of anthraquinone 2-carboxylic acid modified horseradish peroxidase on glassy car...

background: epigenetic reprogramming of differentiated cells can modify somatic cells into pluripotential state. pluripotency can be induced in somatic cells by several approches. one of the easy ways to induce pluripotency is the exposure of the somatic cells to the embryonic stem cell (esc) extract. objective: the objective of this study was to increase the efficiency of reprogramming of gran...

Let $L$ be a completely regular frame and $mathcal{R}L$ be the ‎ring of continuous real-valued functions on $L$‎. ‎We show that the‎ ‎lattice $Zid(mathcal{R}L)$ of $z$-ideals of $mathcal{R}L$ is a‎ ‎normal coherent Yosida frame‎, ‎which extends the corresponding $C(X)$‎ ‎result of Mart'{i}nez and Zenk‎. ‎This we do by exhibiting‎ ‎$Zid(mathcal{R}L)$ as a quotient of $Rad(mathcal{R}L)$‎, ‎the‎ ‎...