BBB blood-brain barrier BMEC brain microvascular (capillary) endothelial cells CBSA cationic bovine serum albumin CdTe cadmium tellurium CTAB trimethylammonium bromide DRG dorsal root ganglia HSA human serum albumin ip intraperitoneal iv intravenous MWCNT multi-walled carbon nanotube PAMAM poly(amidoamine) PBCA polybutylcyanoacrylate PEG polyethylene glycol PLA poly(lactide) PLGA poly(lactic-co...

Targeted drug delivery to endothelial cells lining the vasculature can improve treatment of many pathologies. Intercellular adhesion molecule-1 (ICAM-1), a transmembrane glycoprotein overexpressed in many diseases, is a good determinant for endothelial targeting of drug nanoparticles (NPs). In this study we synthesized surfactant-free, FITC-labeled poly(lactic-co-glycolic) acid (PLGA) NPs coate...

The aim of the present study is to evaluate the potential differentiation ability of gingiva originated human mesenchymal stem cell in the presence of tacrolimus. Tacrolimus-loaded poly(lactic-co-glycolic acid) microspheres were prepared using electrospraying technique. In vitro release study of tacrolimus-loaded poly(lactic-co-glycolic acid) microspheres was performed in phosphate-buffered sal...

The use of mixtures of synthetic and natural polymers is a potential option to reduce the pollution by plastic waste. In this work, the method for the chemical modification of chitosan with poly(lactic acid) was developed; then, the preparation of films of blends of polyethylene and chitosan-poly(lactic acid) produced by an extrusion method using polyethylene-graft maleic anhydride as a compati...

Foreign body reactions may occur in patients who receive bioabsorbable implants during orthopedic surgery for fractures and ligament repair. The authors describe a 34-year-old man who presented with a palpable tender mass on the lateral aspect of the left knee of 1 month's duration. He underwent posterior cruciate ligament and posterolateral corner reconstruction 3 years earlier. Physical exami...

Absorbable plates are used widely for fixation of facial bone fractures. Compared to conventional titanium plating systems, absorbable plates have many favorable traits. They are not palpable after plate absorption, which obviates the need for plate removal. Absorbable plate-related infections are relatively uncommon at less than 5% of patients undergoing fixation of facial bone fractures. The ...

Efficacy of poly (lactic-co-glycolic acid) microparticles as a gonadotropin-releasing hormone analogue delivery system to stimulate ovulation peled Coregonus | Jindriška Knowles, Jakub Vysloužil, Jan Muselík, Vlastimil Stejskal, Kouřil, Peter Podhorec Agricultural Journals

Poly(lactic acid) is a promising biopolymer but due to its low heat deflection temperature, the usage of PLA-based products limited. In case bulk products, annealing an effective way increase temperature. Our aim was improve temperature poly(lactic foams by annealing. this study, we showed that D-lactide content affects crystallinity foam structures in same it PLA. Lower resulted higher degree ...

the purpose of this study was to investigate the effect of additives, poly(ethylene glycol) (peg) 1450, poloxamer 407, polyvinyl alcohol (pva) and sodium chloride in order to improve physico-chemical characteristics, encapsulation efficiency and in vitro release of bovine serum albumin, form poly(d,l-lactic-co-glycolic acid) (plga) microparticles prepared by the w/o/w solvent evaporation method...

Well-controlled poly(alpha-hydroxyacids) featuring pendant carboxylic acid groups were prepared under mild conditions via DMAP-catalyzed ROP of the O-carboxyanhydrides derived from glutamic and lactic acids.