The sympathetic nervous system controls bone remodeling by regulating bone formation and resorption. How nerves and bone cells influence each other remains elusive. Here we modulated the content or activity of the neuropeptide Vasoactive Intestinal Peptide to investigate nerve-bone cell interplays in the mandible periosteum by assessing factors involved in nerve and bone behaviors. Young adult ...

BACKGROUND: Aggressive carcinomas of the scalp usually occur in elderly patients with multiple comorbidities. Complete excision of this type of tumor often involves the removal of periosteum, and the resulting defects can be difficult to reconstruct. OBJECTIVE: To evaluate the usefulness of porcine type I collagen dressings as adjunct or definitive treatment in the surgical closure of scalp def...

BACKGROUND The distal saphenous nerve is commonly known to provide cutaneous innervation of the medial side of the ankle and distally to the base of the great toe. We hypothesize that the saphenous nerve innervates the periosteum of the medial malleolus and joint capsule. METHODS Five fresh limbs were dissected and the saphenous nerve was traced distally with magnification. The medial malleol...

In an experimental study using the Göttingen minipig, Gore-Tex, Gore Resolut, and Vicryl barrier membranes were tested for their efficacy in guided bone regeneration. The results were compared to those of autologous periosteum. The strongest reossification was seen in the bone defects covered with Gore-Tex; however, time-dependent disintegration phenomena, which had already been observed in pre...

Enneking et al. examined the process of local spread of primary bone and soft tissue tumors of the extremities and proposed a “surgical staging system” and “the concept of compartment and anatomic barriers.”17 Applying this concept to the spine, we studied the histology of 19 vertebral tumor specimens resected by TES. We found that the following tissues served as barriers to spinal tumor progre...

DESCRIPTION A 31-year-old man with known history of paraplegia presents to clinic with a long-standing wound as shown earlier. The wound is located in the presacral region with intact periosteum, healthy overlying fascia, and no purulence.

BACKGROUND The histological characteristics of periosteum make it a specific tissue with a unique capacity to be engineered. Higher flexibility of the greater omentum is useful for reconstructive surgery as it facilitates not only filling of the site of infections such as myelitis, but also is effective in filling complicated defects of the soft and hard tissues, and these criteria make it suit...

P hyseal or growth plate injuries comprise 18% of all pediatric fractures, with Salter Harris type II as the most common type of fracture injury pattern observed in 61% of patients. The incidence of growth arrest is just over 1%, and the incidence of serious complications is less than 1%. Irreducible physeal fractures, caused by entrapment of the periosteum, tendons or ligaments, are of particu...