Recombinant activated factor VII (rFVIIa) is a pro-haemostatic agent that can be used for patients with haemophilia and inhibiting antibodies towards a coagulation factor. Recombinant factor VIIa is, however, increasingly used for several other indications, including patients who experience serious and life-threatening bleeding. In addition, rFVIIa has been evaluated for the prevention of major...

End-stage renal disease (ESRD) and chronic kidney disease (CKD) are increasing health problems worldwide. In the US alone, an estimated 26 million people suffer from some form of CKD. In countries such as India and Pakistan, the prevalence of CKD is also rapidly rising. The presence of CKD is associated with increased perioperative morbidity and mortality, even when adjusted for other variables...

Since being introduced over a decade ago, the prostaglandin analog class of medications has revolutionized medical therapy for the glaucoma patient. These agents are commonly used for initial glaucoma therapy in areas of the world where they are readily available and affordable. The popularity of this class stems from several attributes including a high level of effectiveness in lowering IOP, c...

AIM To properly assess the guidance for perioperative management, we undertook a clinical epidemiology study with the primary aim of evaluating the incidence of perioperative vascular complications and their associated factors in a cohort of Japanese patients who underwent non-cardiac surgery in a tertiary medical care center. METHODS This observational study comprised two parts. In the first...

Children are not just 'small adults'. They have specific physical, psychological and social requirements that must be identified and addressed to optimise their well-being in the perioperative period. The healthcare practitioner should be trained to understand the needs of the paediatric patient in hospital, including the ever increasing need to take into account cultural differences. Hospital ...

the case report that will be presented is an inherited methemoglobinemia , during general anesthesia of 36year old patient and was suspected by some clinical xamination such a decrease oxygen saturation in pulse oximetry and a normal finding in abg sample that have been prepared at the preparation of patient for anesthesia .so we are going to write about this problem in the perioperative period...

UNLABELLED OBJECTIVE To investigate anti-infective treatments in HIV-infected surgical patients during the perioperative period. METHODS A retrospective study of sepsis and surgical site infections (SSIs) was conducted in 266 HIV-infected patients. The patients were divided into 3 groups based on CD4+ T cells counts in the preoperative period: group A (0-199 cell/ul), group B (200-349 cell...

Throat packs are documented to cause airway obstruction [1-3]. There have several instances in the literature exploring obstruction of airway and other complications by pharyngeal packs [1-4]. They are commonly associated with throat pain and mucosal injury [4]. Besides their main use to prevent aspiration, throat packs can also lead to complications e.g. retained/forgotten throat packs, oedema...

Editor’s key points † Diabetes mellitus and other disorders of blood glucose regulation are common in perioperative patients. † The optimal management of perioperative dysglycaemia has been shown to improve perioperative outcomes. † Guidelines and recommendations aid in the diagnosis and management of perioperative abnormalities in glucose homeostasis. Summary. The prevalence of type 2 diabetes...

BACKGROUND Immobilisation, blood loss, sleep deficiency, and (concomitant) medications during perioperative periods might lead to acute exacerbation of symptoms in patients with the restless legs syndrome (RLS). Continuous transdermal delivery of the dopamine agonist rotigotine provides stable plasma levels over 24 h and may provide RLS patients with a feasible treatment option for perioperativ...