Abolishing the threat of nuclear war requires the outlawing of nuclear weapons and dismantling current nuclear weapon stockpiles, but also depends on eliminating access to fissile material (nuclear weapon fuel). The near-universal use of weapons-grade, highly enriched uranium (HEU) to produce radiopharmaceuticals is a significant proliferation hazard. Health professionals have a strategic oppor...

The Nuclear Notebook is researched and written by Hans M. Kristensen, director of the Information Project with Federation American Scientists, Matt Korda, a senior research associate project. column has been published in Bulletin Atomic Scientists since 1987. This issue’s examines Israel’s nuclear arsenal, which we estimate includes stockpile roughly 90 warheads. Israel neither officially confi...

objective adenoid cystic carcinoma (acc) is a rare malignant tumor originating from the salivary glands. it’s rather bland histological appearance that masks its ultimate biological aggressiveness. evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. the aim o...

Twenty-nine canine cutaneous mast cell tumors (MCTs) were morphometrically analyzed with regard to mean nuclear area (MNA) using cytopathology smears. The results showed a correlation between MNA and survival. When graded into 2 morphometrically different groups, there were statistically significant differences among high- and low-grade MCTs, regarding both Romanowsky-type stain and hematoxylin...

High-grade squamous intraepithelial lesion (HSIL) smear is one of the categories of squamous cell abnormality in the 2001 Bethesda System. HSIL denotes cases who have abnormal squamous cells with an increased nuclear/ cytoplasmic ratio, marked atypical nucleus, and irregular nuclear border (Wright et al., 2011). At the present, HSIL is acknowledged as a high-grade cervical smear abnormality. Ac...

In a series of 104 patients with renal cell carcinoma, a variety of clinical and histological factors were analyzed to establish their value as prognostic factors. In a univariate analysis (log-rank test), the presence or absence of symptoms, tumor size, pT, N, M, pV categories, TNM stage, Robson stage, nuclear grade and cell type were significantly associated with cause-specific survival, whil...

Tumor grade, size and margin status are the most significant factors in predicting the behavior of ductal carcinoma in-situ (DCIS). The inclusion of necrosis and nuclear grade in the grading of DCIS has demonstrated a fair but suboptimal agreement between pathologists. The grading of DCIS was studied and compared to the Van Nuys (VN) system, by using our newly proposed unifying "nuclear grade +...

INTRODUCTION TRAIL protein may serve as an escape mechanism for cancer cells from the immune response. The aim of the study was to assess whether the presence of TRAIL protein correlates with unfavourable prognostic factors in breast carcinoma. MATERIAL AND METHODS The study group was composed of breast cancer patients treated surgically in the Department of Surgical Oncology, Medical Univers...