A pressure gradient caused by the local field-induced reduction of effective molecular volume results in a flow nematic liquid crystal (NLC). Here, hydrodynamics homeotropically aligned NLC molecules under influence this was studied theoretically. The equations describing system were written and solved steady-state case using analytical methods, stationary velocity observed found. We discussed ...

BACKGROUND In hepatocellular carcinoma (HCC), different signaling pathways are de-regulated, and among them, the expression of the epidermal growth factor receptor (EGFR). Tyrphostin AG-1478 is a lipophilic low molecular weight inhibitor of EGFR, preferentially acting on liver tumor cells. In order to overcome its poor drug solubility and thus improving its anticancer activity, it was entrapped...

BACKGROUND Lipid-based nanosystems have great potential for transdermal drug delivery. In this study, nanostructured lipid carriers (NLCs) for short-acting alkaloids lappacontine (LA) and ranaconitine (RAN) isolated from Aconitum sinomontanum (AAS) at 69.47 and 9.16% (w/w) yields, respectively, were prepared to enhance percutaneous permeation. Optimized NLC formulations were evaluated using uni...

Given its advantages in skin application (eg, hydration, antiaging, and protection), argan oil could be used in both dermatological and cosmetic formulations. Therefore, the preparation of nanostructured lipid carriers (NLCs) using argan oil as a liquid lipid is a promising technique, since the former constitute well-established systems for dermal delivery. The aim of this work was to develop a...

Nanostructured lipid carrier (NLC) is the blend of solid lipid, liquid lipid and suitable surfactant for the purpose of encapsulated poorly water soluble drugs. [6]-gingerol is the main bioactive compound in Zingiber officinale, widely known as ginger in Malaysia. Zingiber officinale extract has been discovered to have anti-oxidant, anti-inflammatory, and anti-microbial effects to human body. T...

PURPOSE Oxidative stress is implicit in the pathological changes associated with glaucoma. The purpose of this study was to compare levels of oxidative stress in glial fibrillary acid-negative protein (GFAP) lamina cribrosa (LC) cells obtained from the optic nerve head (ONH) region of 5 normal (NLC) and 4 glaucomatous (GLC) human donor eyes and to also examine mitochondrial function and calcium...

Purpose: Nanostructured lipid carriers (NLCs) composed of solid lipid and oil are a new generation of lipid nanoparticles which have exhibited some merits over traditional used lipid nanoparticles in fortifying food and beverages and nutraceuticals delivery systems such as liposomes and solid lipid nanoparticles. Methods: In this study, Precirol and Compritol as solid lipids, Miglyol and Octylo...

A nematic liquid crystal adaptive optics system (NLC AOS) was assembled for a 2.16-m telescope to correct for atmospheric turbulence. LC AOS was designed and optimized with Zemax optical software. Second, an adaptive correction experiment was performed in the laboratory to test the performance of the NLC AOS. After the correction, the peak to valley (PV) and root mean square (RMS) of the wavefr...

A high energy e + e − linear collider (NLC) is an excellent tool for studying the properties of the top quark. In this talk I review some of the theory of top quark production and decay in e + e − collisions both at threshold and in the continuum. I also report on the results of phenomenological analyses of t ¯ t production at the NLC.

The aim of this review is to discuss the development nanostructured lipid carrier (NLC) by application quality design (QbD). QbD started with evolution concept and slow adaptation guidelines, which has now become a regulatory requirement. In review, brief history elements including risk assessment (RA) have been discussed followed experiments (DoEs) that acts as tool analyze input whose variati...