BACKGROUND/OBJECTIVE Lipopolysaccharides (LPS) promote allergic responses to nickel (Ni) both in the sensitization and elicitation steps. In this study, we examine the effect of pre-sensitization to LPS on the occurrence of Ni allergy using a mouse model. METHOD A 100 mg of LPS was injected into C57BL/6J mice intraperitoneally (ip). Three weeks later, the mice were subsequently injected with ...

BACKGROUND The epidemiology of contact dermatitis can be analyzed using clinical data from skin allergy units. OBJECTIVES The aims of this study were to define the profile of patients attending a skin allergy unit and to determine the prevalence of the most common sensitizations in this population. MATERIAL AND METHODS Throughout 2008, a retrospective observational study was carried out in ...

This study attempts to determine the incidence of contact allergy in children in Hong Kong and to see if any difference in the incidence of contact allergy exists between children with non-atopic and atopic dermatitis. It also attempts to identify the common contact allergens for children in Hong Kong. 217 children under 16 were classified into non-atopic and atopic dermatitis groups and there ...

The potential of metal-containing orthopaedic prostheses to induce problems through metal allergy taxes dermatologists and orthopaedic surgeons alike. Metal-on-plastic joint replacements are not thought to induce metal allergy but wear products, principally polypropylene particles, produce a foreign body reaction in bone and may lead to aseptic loosening of the joint. Orthopaedic surgeons are i...

OBJECTIVES Evaluation of the allergenic properties of the metal knee or hip joint implants 24 months post surgery and assessment of the relation between allergy to metals and metal implants failure. MATERIALS AND METHODS The study was conducted in two stages. Stage I (pre-implantation) - 60 patients scheduled for arthroplasty surgery. Personal interview, dermatological examination and patch t...

OBJECTIVE The aim of this study based on the records of the dermatology department of a tertiary referral hospital was to describe patients treated for allergic contact dermatitis induced by nickel between 2000 and 2010. MATERIALS AND METHODS From records of the skin allergy section of the dermatology department we extracted and analyzed information for patients who underwent patch testing wi...

BACKGROUND Occupational contact dermatitis is common in healthcare workers. Although irritant contact dermatitis resulting from wet work is the most frequently reported cause, healthcare workers also constitute high-risk group for the development of allergic contact dermatitis and contact urticaria. OBJECTIVES To evaluate the prevalence of delayed-type and immediate-type hypersensitivity in 1...

This study aims at comparing conventional and nickel-free metal bracket surface characteristics with elemental composition by scanning electron microscopy (SEM), using energy dispersive spectroscopy (EDS). The sample consisted of 40 lower incisor brackets divided into four groups: ABZ = conventional brackets, Kirium Abzil 3M® (n = 10); RL = conventional brackets, Roth Light Morelli® (n = 10); N...