normal 0 false false false en-us x-none fa microsoftinternetexplorer4 in this paper, a fully discretized bio-fidelity simulation model for bio-mechanical (kinematic) analysis of scoliosis for various patients was developed to analyze forces on vertebrae, loads acting on the intervertebral disc, corresponding angles between vertebrae, and tension in the spine muscles during lateral bending. it w...

Esophageal transport is a physiological process that mechanically transports an ingested food bolus from the pharynx to the stomach via the esophagus, a multilayered muscular tube. This process involves interactions between the bolus, the esophagus, and the neurally coordinated activation of the esophageal muscles. In this work, we use an immersed boundary (IB) approach to simulate peristaltic ...

(1) In many models muscle force can instantaneously drop to zero or rise to maximal force (e.g. [2]) However, in reality muscular dynamics will prevent such fast transitions in force. (2) Objective functions based on mechanical measures such as muscle force or stress are frequently used (e.g. [3]). However, the validity of these functions is unknown. A recent study posed an energy-related cost ...

Adipose tissue is an abundant, easily accessible, and reproducible cell source for musculo-skeletal regenerative medicine applications. Initial derivation steps yield a heterogeneous population of cells of stromal vascular fraction (SVF) cells. Subsequent adherent selection of the SVF results in a relatively homogeneous population of adipose-derived stromal/stem cells (ASCs) capable of adipogen...

Recent data highlight that competitive skiers face a high risk of injuries especially during off-balance jump landing maneuvers in downhill skiing. The purpose of the present study was to develop a musculo-skeletal modeling and simulation approach to investigate the cause-and-effect relationship between a perturbed landing position, i.e., joint angles and trunk orientation, and the peak force i...