PURPOSE Crotoxin is the major toxin of the venom of the South American rattlesnake Crotalus durissus terrificus, capable of causing a blockade of the neurotransmitters at the neuromuscular junction. The objective of this study was to appraise the action and effectiveness of the crotoxin induced paralysis of the extraocular muscle and to compare its effects with the botulinum toxin type A (BT-A)...

Besides the hereditary hyperkalaemic paralysis, a secondary form exists which often mimicks Guillain-Barre syndrome. A 62 year old patient is reported on who developed severe hyperkalaemic paralysis on the basis of mild renal failure and additive spironolactone intake. Neurophysiological examinations disclosed normal muscle fibre activity but delayed nerve conduction velocities indicating that ...

Evidence indicates that neuroinflammation contributes to motor neuron degeneration in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease leading to progressive muscular paralysis. However, it remains elusive whether inflammatory cells can interact with degenerating distal motor axons, influencing the progressive denervation of neuromuscular junctions (NMJs). By analyzing the...

Research describing physical therapy interventions for patients diagnosed with Ramsay Hunt Syndrome is limited. [1,2]. Ramsay Hunt Syndrome is a rare, devastating diagnosis that involves unilateral peripheral facial paralysis and in some cases vesicular rash on the ear or in the mouth. Physical therapy treatment for facial paralysis includes transcutaneous electrical stimulation, massage, neuro...

Neck ventroflexion in cats has different causes; however, the most common is the hypokalemia associated with flaccid paralysis secondary to chronic renal failure. In humans, the most common causes of acute flaccid paralysis are hypokalemia precipitated by thyrotoxicosis and familial forms linked to mutations in sodium, potassium, and calcium channel genes. Here, we describe the sequencing and a...

Paralysis of skeletal muscles, which can lead to paralysis of respiratory muscles and death, is one of the most toxic effects of organophosphates, and oximes are almost the only known antidotes that can reverse or prevent such toxic effects. In the present research work, possible reversal or preventive effect of different concentrations of the relatively new oxime (HI-6) on changes induced by p...

Paralysis of skeletal muscles, which can lead to paralysis of respiratory muscles and death, is one of the most toxic effects of organophosphates, and oximes are almost the only known antidotes that can reverse or prevent such toxic effects. In the present research work, possible reversal or preventive effect of different concentrations of the relatively new oxime (HI-6) on changes induced by p...

OBJECTIVES/HYPOTHESIS Unilateral vocal fold paralysis with no preceding causes is diagnosed as idiopathic unilateral vocal fold paralysis. However, comprehensive guidelines for evaluating the defining characteristics of idiopathic unilateral vocal fold paralysis are still lacking. In the present study, we hypothesized that idiopathic unilateral vocal fold paralysis may have different clinical a...

background and aims: ischemic stroke is the most common type of stroke and its most important symptoms are paralysis and movement disorders. therefore, finding a method for treating this disorder is greatly important. this study was conducted to investigate the clinical efficacy of frankincense on the patients with ischemic stroke. methods: in this clinical trial study, 60 patients with ischemi...

Tetraparesis is more often a clinical feature of profound hypokalaemia 1, 2 than hyperkalaemia. Neurological features ofhyperkalaemia are rarely seen in clinical practice, as they are precluded by cardiotoxic complications such as arrhythmias. However, patients may develop flaccid paralysis of skeletal muscle with areflexia mimicking symptoms of acute inflammatory demyelinating polyneuropathy.3...