A broad spectrum of health benefits from intermittent fasting have been reported in studies on animal models and human subjects. However, the underlying mechanisms these beneficial effects remain largely elusive. The present study aimed to explore potential mode action mouse with a focus liver. C57BL/6 mice were subjected or ad libitum feeding as controls. It was determined that 12 h d...

With the prevalence of obesity and obesity-related metabolic syndrome, such as insulin resistance in recent years, it is urgent to explore effective interventions prevent progression syndrome. Palmitoleic acid a monounsaturated fatty that available from dietary sources, mainly derived marine products. plays positive role maintaining glucose homeostasis reducing inflammation. However, still unkn...

in current study, a few sheep cystic livers and lungs were obtained from mashhad slaughter house and protoscolex were separated aseptically. thirty 6-week-old swiss mice were divided into 5 groups and two thousands of live protoscolices were inoculated intrapritoaneally in each mouse. in group 1 and 2 (prophylactic groups), mice were given 150 mg/kg of oral albendazole and mebendazole for 10 da...

Microbial resistance towards antibiotic is menacing all over the world and therefore considered to be a global health issue. Their potentialities for adapting new mechanisms threaten our ability treat common infectious diseases. Hence it important explore alternative therapies combat microbial Among them, honeybee products comprise wide variety of dietary/nutritional supplements with range phar...

conclusions based on our results, the administration of fe3o4-nps causes dose dependent adverse effects on liver. background because of their unique magnetic properties, fe3o4 nanoparticles (fe3o4-nps) have extensive applications in various biomedical aspects. investigation of the possible adverse aspects of these particles has lagged far behind their fast growing application. objectives the cu...

Quercetin is the most abundant flavonoid molecules, widely distributed in the plant kingdom and has a wide range of uses. The aim of the study was to determine the LD50 of onion skin quercetin (OSQ) and its effect on the liver and kidney of mice. The study consists of 2 phases. In phase 1, nine mice BALB/c were divided into three groups of three mice each. The mice in each group received OSQ at...

objective(s):fuzheng huayu recipe (fzhy) exerts significant protective effects against liver fibrosis by strengthening the body’s resistance and removing blood stasis. however, the molecular mechanisms through which fzhy affects liver fibrosis are still unclear. in this study, we examined the expression levels of factors involved in the inhibitor κb kinase-β (ikk-β)/nuclear factor-κb (nf-κb) an...

objectives: toxoplasma gondii is a coccidian protozoon which forms tissue cyst in different organs of infected intermediate host. the present study was conducted to demonstrate the active form of parasite in different tissues of rat, which was experimentally infected with rh strain of toxoplasma gondii using bioassay method inmice. materials & methods: in the experimental assay, 75 rats an...

• A MIF antagonist, ISO-1, protected mice from acute acetaminophen (APAP)-induced liver injury. The effect of ISO-1 may be involved in the recover GSH depletion and inhibition up-regulation RIPK3 kinase following oxidative stress by APAP liver. As an additional on APAP-liver injury, inhibit development further expansion excessive neutrophilic responses. Overdose use (APAP) often occurs a severe...