OBJECTIVES The aim of this study was the scintigraphic evaluation of clinical no-reflow phenomenon. BACKGROUND In patients with acute myocardial infarction, the relationship of the severity of reduction of microvascular reflow to the ischemia time or to the secondary extension of myocardial necrosis is poorly understood, and we accordingly conducted a scintigraphic evaluation of clinical no-r...

PURPOSE To determine (a) whether superselective angioscintigraphy with technetium-99m macroaggregated albumin (99mTc-MAA) can be used for the evaluation of arteriovenous shunting in tumors and vascular malformations of the head and spine and (b) whether the amount of microparticles shunted is related to diagnosis, lesion size, or angiographic pattern. METHODS Particles of 99mTc-MAA with a cal...

BACKGROUND AND STUDY AIMS Chronic liver disease (CLD) can cause hepatopulmonary syndrome (HPS), defined as triad of liver disease, hypoxemia, and intrapulmonary vascular dilation (IPVD). The aim of this study was to determine the evidence of IPVD in a cohort of pediatric patients with CLD pre- and post-liver transplantation (LT). MATERIAL AND METHODS All pediatric patients with CLD listed for...

Peritoneal dialysis (PD) is an established renal replacement therapy for patients with end-stage renal disease (ESRD), and it is an effective mean of treatment for maintaining patients' residual renal function and their quality of life (QOL). However, acute hydrothorax is one of the complications of PD that can lead to discontinuation of PD and a switch to hemodialysis. We report a case of a 5...

Hepatopulmonary syndrome is defined as the clinical triad of advanced liver disease, arterial deoxygenation and intrapulmonary vascular dilatation. Its pathogenesis is not completely understood. Excessive pulmonary nitric oxide production seems to be one of the factors that contribute to the intrapulmonary vascular dilatation. Other mediators such as endothelin-1 and the heme oxygenase-1/carbon...

Attenuation correction is necessary for quantification in micro-single-photon emission computed tomography (micro-SPECT). In general, this is done based on micro-computed tomographic (micro-CT) images. Derivation of the attenuation map from magnetic resonance (MR) images is difficult because bone and lung are invisible in conventional MR images and hence indistinguishable from air. An ultrashor...

Utilizing the 1311-MAA (macroaggregated albumin labeled with iodine-131) scintillation scanning method, regional pulmonary blood flow distribution was studied in 47 cardiac patients with pulmonary hypertension. Remarkable increase of blood flow in the upper zones of the lung together with decrease in the lower zones was found in the majority of the patients with mitral valve disease, while in t...

Chronic lung disease is a major worldwide health concern but better tools are required to understand the underlying pathologies. Ventilation/perfusion (V/Q) single photon emission computed tomography (SPECT) with per-voxel analysis allows for non-invasive measurement of regional lung function. A clinically adapted V/Q methodology was used in healthy mice to investigate V/Q relationships. Twelve...

INTRODUCTION Hepatopulmonary syndrome is a rare disease that affects patients of any age with acute or chronic liver disease. Liver transplantation is the only therapeutic option of proved benefit, and can result in substantial improvement or total improvement in postoperative gas exchange abnormalities. CASE PRESENTATION We report the case of a cyanotic 13-year-old Pakistani boy whose chest ...

In order to exclude acute pulmonary embolism, a lung perfusion scintigraphy was performed in a 53-year-old male, with a history of Fallot’s tetralogy. He had been immobilized because of a tibial fracture and complained of worsening chest pain and dyspnea. Since there was no adequate venous access on the right side, the tracer (99mTclabeled macroaggregated albumin or 99mTc-MAA) was injected in a...