Background and Aims Obesity has become the main public health issue nowadays with poor control and has been associated with increased risk of multiorgan disease, but the specific mechanism and effective medication are still to be addressed. Sheng-jiang powder (SJP) showed great potential in preventing obesity in Chinese researches but has no trace in English reports. This study was designed to ...

This study investigated the expectorant effects of immature Asian pear extract (IAP; Pyrus pyrifolia Nakai) on subacute pulmonary injuries in Balb/c mice induced by particulate matter with a diameter approximately 2.5 μm (PM2.5). IAP was administered at three doses, namely, 400, 200, and 100 mg/kg. The body weight gain changes, lung weights, surface gross inspections, tracheal secretions, subst...

Several infectious pathologies in humans, such as tuberculosis or SARS-CoV-2, are responsible for tissue lung damage, requiring regeneration. The regenerative capacity of adult mammals is limited to few organs. Critical injuries non-regenerative organs trigger a repair process that leads definitive architectural and functional disruption, while superficial wounds result scar formation. Tissue l...

Bronchopulmonary dysplasia (BPD) continues to be the most common and most important complication in preterm infants with RDS. The incidence varies from 20 to 60 % in preterm infants whose weight are < 1500 gram. The presence of BPD is often associated with significant mortality and short term and long term morbidity, including growth failure and neurodevelopment delay. The exact mechanism and p...

conclusions results of this study indicate that selective brain cooling is an effective method of decreasing icp in rats; however, the deeper hypothermia caused a greater decrease in icp three hours after hypothermia induction. background experimental approaches have been promising with the use of therapeutic hypothermia after traumatic brain injury (tbi) whereas clinical data have not supporte...

Background. Gunshot injuries occupy one of the leading places in a number (combat injuries) that occur military conflicts.&#x0D; Aim. To study effect gunshot wounds chest (penetrating and non-penetrating), as well closed trauma on respiratory function.&#x0D; Materials methods. The included 78 patients with diagnosis combined trauma, including penetrating/non-penetrating wound or injuries. media...

In April, 1959, at the annual meeting of the American Association for Thoracic Surgery, Hood and Sloan presented an analysis of all cases of injuries of the trachea and major bronchi since the review by Kinsella in 1947. They noted that pulmonary resection had been utilized far too often in recent years and emphasized that repair of such injuries without sacrifice of lung tissue is feasible in ...

This is the first report in the literature to describe removing war-related cardiothoracic shrapnel using video-assisted thoracoscopic surgery (VATS). War blast caused penetrating thoracic and extremity injuries in 30-year-old man. He was referred to our hospital after stabilization. Magnetic resonance imaging was required to evaluate brachial plexus injury. Large, penetrating shrapnel fragment...

The host inflammatory response is critical in the progression of lung injuries patients with SARS-CoV-2. Corticosteroids (CS) have been widely used as immunomodulating agents, but right timing, dosage and type molecule are unknown. In fact, early use CS could facilitate viral replication late administration may not prevent alveolar damage. Nevertheless, a short high doses stage phase resulted f...

In this study, we assessed the in vivo behavior and toxicology of nanoscale graphene oxide (NGO) in mice after intravenous injection. The influence of a polyethylene glycol (PEG) coating on the distribution and toxicity of the NGO was also investigated. The results show that NGO is mainly retained in the liver, lung, and spleen. Retention in the lung is partially due to NGO aggregation. The PEG...