نتایج جستجو برای: lch

تعداد نتایج: 667  

Journal: :iranian journal of otorhinolaryngology 0
mohammad reza majidi ear, nose and throat research center, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran amir hossein jafarian department of pathology ghaem hospital faculty of medicine, mashhad university of medical sciences, mashhad, iran ayeh shahabi department of otorhinolaryngology, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran

introduction: lobular capillary hemangioma (lch) is a benign lesion of vascular origin. it rarely involves nasal cavity which most commonly manifests as progressive nasal obstruction and epistaxis. case report: in this report we present a case of lch of the nasal cavity which occurred approximately one month after delivery. there was no recurrence after complete endoscopic resection during one ...

2016
Hesam Jahandideh Yasser Nasoori Sara Rostami Mahdi Safdarian

Langerhans cell histiocytosis (LCH) is a very rare condition that commonly affects the head and neck region. There are very few cases of isolated laryngeal involvement by LCH, mostly reported in pediatric patients. Here, we report a case of laryngeal LCH in a 62-year-old woman presenting with a neck mass several weeks ago. The clinical and histopathological findings are reported with a brief di...

2016
Liane Gambirazi Tatiana Libório Fábio Nunes Norberto Sugaya Dante Migliari

This article reports a case of oral mucosa lesions as the sole manifestation in Langerhans cell histiocytosis (LCH). This is a very uncommon manifestation of LCH since this disease preferably affects the bones with frequent involvement of the jaws. LCH may also involve other organs, particularly the lungs, liver, lymph nodes, and skin. The highlights of this report are the differential diagnosi...

2012
Shinsaku Imashuku Akira Morimoto

Central diabetes insipidus (CDI) is caused by a deficiency of arginine vasopressin (AVP), also known as antidiuretic hormone. Although CDI is rare in children and young adults, it should be kept in mind that it is associated with rare histiocytic disorders in the central nervous system (CNS), namely Langerhans cell histiocytosis (LCH), xanthogranulomatosis and Erdheim-Chester disease, all of wh...

2016
Caroline Hutter Milen Minkov

More than a century after its first description, Langerhans cell histiocytosis (LCH) still remains an intriguing disease. Considerable progress in understanding its biology has been achieved recently. Description of the V600E BRAF mutation in samples of LCH tissue in 2010 was followed by description of additional mutations, all leading to constitutive ERK activation. Current experimental data s...

Journal: :The Laryngoscope 2016
Mara C Modest Joaquin J Garcia Carola S Arndt Matthew L Carlson

OBJECTIVES/HYPOTHESIS Evaluate presentation, management, and clinical outcomes of patients with temporal bone Langerhans cell histiocytosis (LCH). STUDY DESIGN Retrospective chart review. METHODS Reviewed all patients with temporal bone LCH at a tertiary academic referral center between 1978 and 2014. Presentation, disease course, intervention, and clinical outcomes were analyzed. RESULTS...

Journal: :Polski przeglad chirurgiczny 2012
Pantea Tajik Shiva Nazari Hazhir Javaherizadeh

Langerhans cell histiocytosis (LCH), a monoclonal disease of histiocytes, may involve several organ systems but rarely primarily involves the thyroid gland. This report presents an extremely rare case of LCH of the thyroid in a 3-year-old boy who presented with a neck mass for several weeks. LCH of the thyroid should be considered in the differential diagnosis of a child with a thyroid mass. Pu...

2013
Olga L. Bohn Julie Teruya-Feldstein Sergio Sanchez-Sosa

This chapter reviews the clinical presentation, histopathology, immunoprofile and molecular features of Langerhans cell neoplasms of the skin including Langerhans cell histiocytosis (LCH) and its malignant counterpart, Langerhans cell sarcoma (LCS). Biopsy of the skin is a useful method to confirm LCH/LCS diagnosis, as cutaneous involvement is seen in more than 50% cases. Skin can be the only p...

Journal: :Oncology reports 2015
Ichiro Murakami Jean Gogusev Francis Jaubert Michiko Matsushita Kazuhiko Hayashi Ikuo Miura Takehiro Tanaka Takashi Oka Tadashi Yoshino

A cell line named PRU-1, derived from a Langerhans cell (LC) histiocytosis (LCH) skull lesion of a 7-year-old boy, was established and characterized. PRU-1 is an adherent spindle-shaped cell line that shows no Birbeck granules on electron microscopy. Flow cytometric analysis of cells collected from the early seventh passage showed no LC phenotypes of CD1a and S100 protein. Immunostaining of PRU...

Journal: :International Journal of Modern Physics A 2005

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