نتایج جستجو برای: laryngeal carcinoma cell line

تعداد نتایج: 2174255  

2015
Tarek Assi Elie El Rassy Amine Haddad Joseph Kattan

The urogenital tract is a rare origin of laryngeal metastasis; transitional cell carcinoma with laryngeal metastases had never been reported previously. In this paper, we describe the clinical and pathological characteristics, evolution, and treatment of the first reported case of a laryngeal metastasis of a TCC followed by a brief review of the literature.

Journal: : 2023

Introduction . The histone methylation regulates gene expression and plays a role in genomic stability participating DNA repair. Dimethylation of 3 lysine 36 (H3K36me 2 ) is an important modification which responsible for activation. H3K36me product methyltransferase activity NSD1, NSD2, NSD3, ASH1L proteins. NSD1 mutations are known to often occur head neck squamous carcinoma. presence highly ...

Journal: :Archives of oral biology 2016
Shaimaa M Masloub Mohamed H Elmalahy Dina Sabry Wael S Mohamed Sahar H Ahmed

PURPOSE The purpose of this study is to assess the effect of 5-fluorouracil nanoparticles and curcumin naoparticles on cell proliferation and the expression of the apoptotic marker (caspase 3) in squamous cell carcinoma cell line. MATERIAL AND METHODS PLGA 5-fluorouracil nanopartciles and PLGA curcumin nanoparticles were prepared and applied for 24 and 48h on human laryngeal squamous carcinom...

2014
J. Opoku-Buabeng O. Owusu-Afriyie

Carcinoma of the larynx is one of the commonest malignant tumours of the upper respiratory system.The main objective of this study was to highlight the histological pattern and evaluate the occurrence of the malignant tumours of the larynx. This was a retrospective study involving 146 patients aged between 36 to 77 years with an average age of 59.7 years. Patients with symptoms and signs of lar...

Journal: :Genetics and molecular research : GMR 2013
L B Dong G Q Li Z H Tian Z M Wang K Xu

We investigated the expression of Src homology 2 domain-containing phosphatase (SHP-2) in laryngeal carcinoma and its clinical significance. Expression of SHP-2 was detected by immunohistochemical staining in normal mucosal tissues and various grades of laryngeal carcinoma. We looked for possible correlations between expression of SHP-2 in laryngeal carcinoma and clinical staging and lymph node...

Journal: :Folia histochemica et cytobiologica 2009
Roman Paduch Wojciech Rzeski Janusz Klatka

Head and neck tumors are one of the major public health problem all over the world. Cellular response of larynx carcinoma to cisplatin (CDDP) chemotherapy occurs both in cell-interdependent and cell-autonomous pathways. In the first pathway, cytotoxic signal transduction is mediated via gap-junctional intercellular communication (GIJC). CDDP also influence tumor cell migration.The aim of this s...

2012
Pyeko Menach Herbert O. Oburra Asmeeta Patel

Laryngeal squamous cell carcinoma (SCC) is strongly linked to cigarette smoking. It is estimated to account for more than 70% of laryngeal SCCs and up to 89% in combination with alcohol. We wished to determine the prevalence of cigarette smoking and alcohol ingestion among patients with laryngeal squamous cell carcinoma and estimate risk attributed to cigarette smoking and alcohol ingestion. Fi...

Anju M. Santhosh, Ann George, Gifty Jacob, Prinsy Pappachan, Sibi Perumbamkudiyil Ittiyavirah, Sudhi T. Kurian,

The objective of the study was to evaluate the cytotoxic effects of aqueous extract of Cucumis melo fruit on human prostate cancer cell line (PC-3) using MTT and neutral red assays. The crude aqueous extract of C. melo was prepared by cold maceration method, filtered, concentrated and tested on PC-3 cell line. Dose-dependent cytotoxic activities were exhibited on human prostate carcinoma PC...

Anju M Santhosh, Ann George, Gifty Jacob, Prinsy Pappachan, Sibi Perumbamkudiyil Ittiyavirah, Sudhi T Kurian,

The objective of the study was to evaluate thecytotoxic effects of aqueous fruit extract of Cucumis melo in human prostate cancer cell line (PC-3) using MTTand neutral red assays. The crude aqueous extract of C.melo was prepared by cold maceration method, filtered,concentrated and tested on PC-3 cell line. Dose-dependent cytotoxic activitieswere exhibited by human prostate carcinoma PC-3 cell l...

2016
SHAOZHONG WANG JIAN WU YISA SONG HUILING ZHONG

In recent years, the incidence of laryngeal carcinoma has been on the increase. The aim of the present study was to examine the expression level of endothelin-1 (ET-1) in laryngeal carcinoma tissues and to establish its clinical significance. A total of 82 cases of laryngeal carcinoma tissues were examined, of which 27 cases were stage I, 34 were stage II, and 21 were stage III. The normal muco...

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