نتایج جستجو برای: lal
تعداد نتایج: 1049 فیلتر نتایج به سال:
OBJECTIVE To estimate clinical progression and resource utilisation together with the associated costs of managing children and adults with LAL Deficiency, at a tertiary referral centre in the UK. METHODS A retrospective chart review was undertaken of patients in the UK with a confirmed diagnosis of LAL Deficiency who were managed at a LAL Deficiency tertiary referral treatment centre. Patien...
LAL regulators (Large ATP-binding regulators of the LuxR family) constitute a poorly studied family of transcriptional regulators. Several regulators of this class have been identified in antibiotic and other secondary metabolite gene clusters from actinomycetes, thus they have been considered pathway-specific regulators. In this study we have obtained two disruption mutants of LAL genes from S...
Nature abounds in producing a variety of molecules. This is good thing, however, endotoxin detection requirement for an analytical assay “specificity”. Unfortunately, LAL has been found to be increasingly non-specific since the inception its use lieu rabbit pyrogen test. Fortunately, there are viable workarounds terms using Limulus-based testing where non-endotoxin reactive substance false-reac...
The Limulus amoebocyte lysate (LAL) test has replaced about 80% of the use of the rabbit pyrogen test. Ideally, human-based in vitro tests are needed, to replace the remaining use of the rabbit test and the use of the LAL test. The progress of an EU-funded project is described, in which a number of in vitro tests, based on the human fever reaction are passing through a prevalidation study on th...
OBJECTIVE Dental arch form is one of the most important characteristics of dentition. However, this dimension usually receives less attention in diagnosis or treatment planning and orthodontic patients are traditionally classified with regard to their sagittal characteristics. The objectives of this study were to investigate if a relationship exists between the dental arch width (transverse dim...
Lysosomal acid lipase deficiency (LAL-D) is still a little recognized genetic disease with significant morbidity and mortality in children and adults. This document provides guidance on when to suspect LAL-D and how to diagnose it. It is recommended to add lysosomal acid lipase deficiency to the List of differential diagnoses of sepsis, oncological diseases, storage diseases, persistent diarrhe...
Conducted in a U.S. English-to-Speakers-of-Other-Languages (ESOL) preservice teacher education program, this case study aimed to explore dynamic process of teachers’ development language assessment literacy (LAL). By inviting multiple stakeholders, namely teachers, an inservice and her ESOL students, their course instructor, closely examined the interaction among stakeholders during semester-lo...
The study was carried out in order to find out the effect of substitution of wheat flour with sweet potato flour of two local varieties (Local Sada and Local Lal) on the quality of bread. This study was also concerned with the analysis of proximate compositions of sweet potato and results showed that, fresh local sada and local lal sweet potato varieties contained moisture 70.10 and 66.78%; ash...
Disadvantages of the regulatory pyrogen test to assure safety of the end-product Human Serum Albumin (HSA) for parenteral use call for the implementation of an alternative test. In the current study, 16 HSA batches were assayed for pyrogens in parallel with the Rabbit Pyrogen Test, conventional and endotoxin-specific LAL assay and monocyte activation test (MAT). It was found that all HSA batche...
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