Objectives: Desflurane may be useful for ambulatory anesthesia. However, desflurane-induced airway irritability makes its use challenging, especially in children. Ketamine can used to reduce separation anxiety and emergence agitation (EA). ketamine increase bronchial secretions. This study compared desflurane with sevoflurane anesthesia, terms of time EA, preschool children intravenous (IV) pre...

Objective This study aimed to determine if 0.15 mg/kg intravenous (IV) subdissociative ketamine is noninferior 0.3 in emergency department (ED) patients with acute pain. Methods randomized, prospective, double-blinded, noninferiority trial included patients’ age 18 59 years presenting the ED moderate severe Subjects were randomized IV ketamine, ("low" dose) or 0.30 ("high" dose), over 15 minute...

Objective- The objective of the present study was to determine the changes in heart rate, respiratory rate and arterial Oxygen saturation (SpO2) by administration of three drug combinations during upper gastrointestinal endoscopy. Design- Experimental study. Animals- 21 healthy and adults dog were randomly divided into three groups. Procedures- The IV combination of 6.5 mg/kg ketamine and 0....

A 6-yr-old male patient underwent live related left lateral segment liver transplant for cryptogenic cirrhosis with portal hypertension. One month after the liver transplant the patient had an isolated liver transaminases increase. He was posted for percutaneous liver biopsy for suspected graft rejection under general anesthesia. The patient was administered ketamine 7 mg/kg along with glycopyr...

OBJECTIVE To compare three anaesthetic protocols for umbilical surgery in calves regarding adequacy of analgesia, and cardiopulmonary and hormonal responses. STUDY DESIGN Prospective, randomised experimental study. ANIMALS Thirty healthy German Holstein calves (7 female, 23 male) aged 45.9 ± 6.4 days. METHODS All calves underwent umbilical surgery in dorsal recumbency. The anaesthetic pro...

BACKGROUND Nuss surgery is preferred in pectus excavatum repair because this procedure produces excellent cosmetic results and prevents postoperative distressed pulmonary function. However, the procedure causes severe pain due to thoracic expansion. This study was designed to investigate the analgesic effect of small doses of ketamine on an intravenous patient-controlled analgesia (IV-PCA) usin...

BACKGROUND Intravenous (IV), intramuscular (IM), and subcutaneous (SC) are the three most frequently used injection routes in medication administration. Comparative studies of SC versus IV, IM versus IV, or IM versus SC have been sporadically conducted, and some new findings are completely different from the dosage recommendation as described in prescribing information. However, clinicians may ...

BACKGROUND The use of ketamine in children with increased pulmonary vascular resistance is controversial. In this prospective, open label study, we evaluated the hemodynamic responses to ketamine in children with pulmonary hypertension (mean pulmonary artery pressure >25 mm Hg). METHODS Children aged 3 mo to 18 yr with pulmonary hypertension, who were scheduled for cardiac catheterization wit...