normal 0 false false false microsoftinternetexplorer4 the association of solid tumors with idiopathic thrombocytopenic purpura (itp) is rare. however, there have been some case reports indicating an association between breast cancer and itp. in this article four patients with breast cancer and itp are mentioned. the diagnosis of breast cancer was based on the results of biopsy or surgical sampl...

Childhood immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. Most children recover with initial treatment, but the individual course is hard to predict. The objectives were to study the clinical profile of children with Primary ITP and to identify factors that may predict poor response to initial treatment. Methods: It is a retrospective & prospective study done in a tertiary hos...

Clinical definitions and terminology vary greatly in clinical studies on idiopathic thrombocytopenic purpura (ITP). An objective assessment of this heterogeneity may be of interest, providing a basis for standardizing ITP terminology. A systematic review of the recent literature on ITP in adults was carried out. The following items were extracted from the articles for comparison: platelet count...

PURPOSE This study aimed to evaluate the clinical course of childhood immune thrombocytopenia (ITP) and to assess the risk factors for developing chronic ITP. METHODS The records of 64 children diagnosed with ITP from November 2005 and December 2014 at single center were retrospectively analyzed. RESULTS The median age at diagnosis and the median platelet count were 1 year (range, 1 month t...

Immune thrombocytopenia (ITP) is a bleeding disorder in which antibodies and/or T cells lead to enhanced peripheral platelet destruction and reduced bone marrow platelet production. Several reports have observed that ITP is associated with a peripheral deficiency of tolerance-inducing CD4+CD25+FoxP3+ T regulatory cells (Tregs). Using a murine model of ITP, we analyzed Tregs in the spleen and th...

Immune thrombocytopenia (ITP), previously called idiopathic thrombocytopenia purpura, is an autoimmune disorder characterized by a severe reduction in peripheral blood platelet count. In healthy individuals, normal platelet count ranges from 150-450 × 109/L, while in thrombocytopenia counts fall to less than 100 × 109/L.1 In adults, the incidence of ITP is approximately two to four per 100,000....

Immune thrombocytopenic purpura (ITP) patients are at high risk for bleeding complications regarding surgeries involving cardiopulmonary bypass. We report an ITP patient with chronic thromboembolic pulmonary hypertension who underwent uncomplicated pulmonary endarterectomy with receiving postoperative intravenous immunoglobulin (IVIG) therapy. The positive outcome of this case may suggest that ...

This paper describes the detection of a cardiac biomarker, cardiac troponin I (cTnI), spiked into depleted human serum using cationic isotachophoresis (ITP) in a 3.9 cm long poly(methyl methacrylate) (PMMA) microfluidic channel. The microfluidic chip incorporates a 100 crosssectional area reduction, including a 10 depth reduction and a 10 width reduction, to increase sensitivity during ITP. The...

BACKGROUND German data on economic consequences of immune thrombocytopenia (ITP) are limited. PATIENTS AND METHODS A retrospective, observational study based on chart review of adult patients with a confirmed diagnosis of ITP was conducted at a German university hospital. Costs are presented from the hospital perspective. RESULTS Of 50 eligible patients, 45 could be classified by disease du...