background: cardiovascular disease is a major cause of death throughout the world. the aim of this study was to as­sess the prevalence of overweight/obesity, central obesity, hypertension and dyslipidemia, as well as dietary factors contribut­ing to the development of dyslipidemia among middle-aged women. methods: the research design of the present study was a population-based cross-sectional s...

objective(s) primary or adult type hypolactasia, the most common enzyme deficiency in the world, is due to reduced lactase activity in the intestinal cell after weaning. lactase non-persistence is inherited as an autosomal recessive trait. a dna variant, single nucleotide polymorphism c/t−13910 which is located on 13910 base pairs (bp) upstream of the lactase gene (lct) at chromosome 2 has been...

background: omeprazole is metabolized predominantly by cyp2c19, a polymorphically expressed enzymes that show marked interindividual and interethnic variation. these variations cause a substantial differences that have been reported in the pharmacokinetics of omeprazole. the aim of the present study was to evaluate the pharmacokinetic parameters of omeprazole in a random iranian population. met...

BACKGROUND Polycystic ovary syndrome (PCOS) is a complex disease having both genetic and environmental components and candidate genes on obesity and insulin metabolism have been hypothesized to be involved in its etiology. OBJECTIVE We examined the possible association of adiponectin and insulin receptor gene polymorphisms with PCOS. MATERIALS AND METHODS A total of 186 women with PCOS usin...

BACKGROUND In each society, the health of women in different periods may be endangered by an unequal distribution of resources, facilities, and gender prejudices. The present study evaluated the time trend of Iranian women's health between 1990 and 2013. METHODS This narrative review includes an integration and descriptive summary of the existing evidence on trends and criteria of different a...

Background and aims: In each society, the health of women in different periods may be endangered by an unequal distribution of resources, facilities, and gender prejudices. The present study evaluated the time trend of Iranian women’s health between 1990 and 2013. Methods: This narrative review includes an integration and descriptive summary of the existing evidence on trends and criteria of di...

BACKGROUND Breast Cancer (BC) is the most common cancer in Iranian women, meanwhile the Iranian patients are relatively young. Granzyme H (GZMH) is a functional cytotoxic serine protease of NK cell granules, which expands the cell death-inducing repertoire of innate immune system. GZMH is constitutively and highly expressed in human NK cells, in order to possess chymotrypsin-like (chymase) enzy...

osteoporosis is a disease of high prevalence with increased bone loss. it has potential public health threat and that the health authorities had taken several measures for its control. in recent years, considerable attention has been given to physiopathology of osteoporosis. oxidative stress has been proved to be involved in bone resorption. oxidative stress occurs when balance between oxidants...

Sexual health and rights indicators provide essential tools for monitoring the status of individuals' sexual health and its rights, in various countries. This paper discusses sexual health and rights indicators in Iran. The indicators under study are derived from similar indicators developed by Asian-Pacific Resource and Research Center for Women, for the 15th anniversary of the International C...