Tolerogenic dendritic cells (DCs) are potential cell-based therapy in autoimmune diseases. In this study, we generated alternatively activated DCs (aaDCs) by treating monocyte-derived DCs from patients with systemic lupus erythematosus (SLE) and healthy subjects with combination of 1,25 dihydroxyvitamin D(3) (vitD3) and dexamethasone followed by lipopolysaccharide-induced maturation. Lupus aaDC...

Fish wastes constitute an important source of biologically active molecules possessing peculiar properties and practical application promises in various areas ( agriculture, medicine, chemistry, biotechnology ). Several enzymes from crustacean and fish wastes for which sizable stocks of viscera are actually available have been considered. These enzyme activities are namely an aminopeptidase fro...

There is no malaria vaccine currently available, and the most advanced candidate has recently reported a modest 30% efficacy against clinical malaria. Although many efforts have been dedicated to achieve this goal, the research was mainly directed to identify antigenic targets. Nevertheless, the latest progresses on understanding how immune system works and the data recovered from vaccination s...

Aquaculture is a rapidly growing global agriculture sector and the importance of fish health has become of upmost importance as production levels and stocking densities increase. Over the past few decades, there have been a large number of immunological investigations on commonly cultured finfish species. Further, new technologies and strategies that embody use of fish immunostimulants, probiot...

This study was conducted to investigate the effects of Curcuma zedoaria and Zingiber zerumbet on non-specific immune responses of grouper (Epinephelus coioides). Fish were fed an experimental diet containing 0, 0.5, 1.0, 2.5 g/kg of C. zedoaria and Z. zerumbet mixed diets twice daily for two weeks. Non-specific immune parameters such as respiratory burst activity, reactive oxygen species, phago...

There is an increasing interest in the use of insects animal feed since they contain high proteins levels, lipids, vitamins and minerals. In particular, insect-derived are seen as one potential solution to face protein shortage able fully substitute soybean meal or fishmeal aquaculture livestock feeds. However, beside their interesting nutritional composition, also rich bioactive compounds such...

Aeromonas hydrophila (A. hydrophila) are classified as zoonotic and opportunistic bacteria. Natural immunostimulants such herbs biodegradable safe for the environment host health. There has been no systematic review of using these natural ingredients to treat or prevent A. infection. This aims demonstrate role probiotics antibacterial, antioxidant, immunostimulatory against study deployed compr...