BACKGROUND Psoriasis is a chronic inflammatory immune disease with undefined pathogenesis. It is associated with T cells, and the IL-23/IL17 axis is believed to be crucial in the pathogenesis. The present treatments have side effects that influence the compliance of patients. Tea polyphenol is extracted from tea polyphenols, and its main active ingredient is Epigallocatechin-3-gallate (EGCG), w...

BACKGROUND Trauma is associated with altered host defense and susceptibility to infection, in part due to cytokine dysregulation and altered T-cell immunity. The gut-associated lymphoid tissue (GALT) provides a defense against infection and contributes to the process of mucosal healing by T-cell activation and cytokine production. OBJECTIVE To determine whether femur fracture induces alterati...

Vitamin D is a fat-soluble vitamin, formed in the skin under action of UVB light and known as sunshine vitamin with immunomodulatory well classical endocrine actions calcium control. It has role both innate adaptive immune responses. Intracellular synthesis 1,25(OH)D immunocytes promotes production cathelicidin human b -defensin-2 which are …..antimicrobial peptides produced by neutrophils, mac...

There is good evidence that, in agreement with the principles of clonal selection, the immunoglobulin molecules synthesized by one B immunocyte, or by a clone of these cells, are uniform with regard to the Fv portion; that is, they have a uniform antibedy-combining site and a uniform idiotype (reviewed by Makela and Cross 1970). This condition applies beth to the membrane-bound immunoglobulins ...