persistent microalbuminuria is predictive of nephropathy in patients with type i diabetes mellitus (dm) and has led to the development of screening programs and intervention studies. we report a longitudinal evaluation of urinary albumin excretion in 118 children with type i dm, attending a single clinic over a period of seven years. collected blood and urine samples were analyzed for glycated ...

Hemoglobin A1c (HbA1c) is used routinely to monitor long-term glycemic control in people with diabetes mellitus, as HbA1c is related directly to risks for diabetic complications. The accuracy of HbA1c methods can be affected adversely by the presence of hemoglobin (Hb) variants or elevated levels of fetal hemoglobin (HbF). The effect of each variant or elevated HbF must be examined with each sp...

The study was to examine the effects of a six-month educational program aiming acquisition of self-management skills on patients with diabetic nephropathy. One-group, pre- and post-test design was performed. Face-to-face and telephone interviews were conducted by nurses. Thirty participants completed the program. As a result of the program, self-efficacy, self-management ability, and Hb(A1c) im...

Labile hemoglobin A 1c (Hb A 1c), or pre–Hb A 1c , is an intermediate in the synthesis of Hb A 1c and is characterized by the reversible binding of glucose to Hb as a Schiff base (1). Its biological variation is related to recent fluctuations in glycemia and cannot provide suitable retrospective information on a patient's long-term glycemic balance. Therefore, labile Hb A 1c must be eliminated ...

BACKGROUND Hemoglobin (Hb) A1c is widely used as the gold standard for blood glucose level monitoring in diabetic patients. Various methods are being used in clinical laboratories for HbA1c measurement. However, the presence of Hb variants may interfere with HbA1c measurement. METHODS The HbA1c assay was performed routinely in a 55-year old woman with type 2 diabetes and hyperlipidemia that w...

AIMS An abnormality in the glycated haemoglobin peak (Hb A1c) on Diastat (Bio-Rad) cation exchange low pressure liquid chromatography (LPLC) was found in three Punjabi patients with diabetes. The aims of this study were to identify the variant by chromatography and electrophoresis and to determine whether a DNA analysis test could be designed for confirmation that could be generally applied for...

OBJECTIVE The aim of this study was to examine the dental condition and oral manifestations in diabetic and nondiabetic uremic patients undergoing hemodialysis. STUDY DESIGN A total of 128 patients undergoing hemodialysis therapy were classified into the diabetic and nondiabetic groups and examined for uremic oral manifestations, dental caries, and the periodontal status. All the patients rec...

OBJECTIVE Hemoglobin A1c (HbA(1c)) has been widely used as a clinically important assessment tool for outcome analyses related to glycemic control. However, because of special conditions in dialysis patients, including the uremic milieu, there is no HbA(1c) blood glucose (BG) equation specific for patients on dialysis. In this study, we sought to develop HbA(1c)-BG equation models for hemodialy...

Brand, Christian L., Jeppe Sturis, Carsten F. Gotfredsen, Jan Fleckner, Christian Fledelius, Bo F. Hansen, Birgitte Andersen, Ji-Ming Ye, Per Sauerberg, and Karsten Wassermann. Dual PPAR / activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats. Am J Physiol Endocrinol Metab 284: E841–E854, 2003. First published December 10, 2002; 10.1152/ajpendo.00348.2...