The different papers in this special issue all addressed learning with complex tasks. All of these papers reached only partially the expected results. This discussion on possible factors that may explain these unexpected results. A first issue that is questioned is the functionality of the tools in the studies. Secondly, the learners lack of compliance is addressed. It may have been that the le...

This study aims to determine the strategy of Ponorogo district government in carrying out various efforts promote or compare culture as a tourist attraction strategy. Therefore organize an event, event management is needed. research method uses library method, namely that collects information and data with help materials available on internet libraries, such reference books, previous similar re...

The discovery of the organizer by Spemann and Mangold in 1924 raised two kinds of questions: those about the means of patterning the chordate body axis and those about the mechanisms of cell determination by induction. Some researchers, stressing the second, have suggested over the years that the organizer is poorly named and doesn't really organize because inducers act permissively, because th...

This paper presents the strategy for multi-criteria optimization of a prototype. There are taken into account two different optimization criteria. An original computer program was made to make possible the graphic display of regions on the 3D model surface, which exceed a limit for surface roughness, initial established. The computer program allows the automate calculation of optimal position f...

MLF is a type system that seamlessly merges ML-style type inference with System-F polymorphism. We propose a system of graphic (type) constraints that can be used to perform type inference in both ML or MLF. We show that this constraint system is a small extension of the formalism of graphic types, originally introduced to represent MLF types. We give a few semantic preserving transformations o...

Maternal Wnt11 is both necessary and sufficient for the formation of Spemann organizer in Xenopus embryo. Xnr3 and Siamois have been identified as the direct target genes of maternal Wnt11/β-catenin during organizer induction. The depletion of maternal XTcf3 resulted in the ectopic expression of Xnr3 and Siamois, suggesting the activity of β-catenin/XTcf3 is strictly regulated in the early Xeno...

The vertebrate organizer has been of intense interest since its discovery in amphibia by Spemann and Mangold in the early 1920s (Ref. 1). The organizer was operationally defined as a piece of tissue that can induce a duplicated dorsal body axis and head when transplanted into the ventral side of a host embryo. The original Spemann and Mangold organizer experiment provided the first convincing d...

nucleolar organizer regions (nor) are defined as nucleolar components containing a set of argyrophilic proteins which are selectively stained by colloidal silver nitrate staining. although studies have shown that the number of nor dots or particles is directly related to the rapidity of cell proliferation in cancer cells, prognostic or diagnostic value of nor remains controversial. the aim of t...

The studies investigated if advance organizer learning will facilitate learning of some selected Government concepts among senior secondary school students in Oyo State, Nigeria. The study assessed the differences in the academic performances from low, middle, and high socio-economic backgrounds of students after they have been exposed to advance organizers learning strategy. The design for the...