Background: Boron Neutron Capture Therapy (BNCT) is a very promising treatment for patients suffering gliobastoma multiforme, an aggressive type of brain cancer, where conventional radiation therapies fail. Thermal neutrons are suitable for the direct treatment of cancers which are located at near-tissue-surface deep-seated tumors need harder, epithermal neutron energy spectra. Materials and Me...

the aim of this study is to provide a control software system, based on monte carlo simulation, and calculations of dosimetric parameters of standard and wedge radiation fi elds, using a monte carlo method. gate version 6.1 (opengate collaboration), was used to simulate a compact 6 mv linear accelerator system. in order to accelerate the calculations, the phase-space technique and cluster compu...

Introduction Polymer gel dosimeters offer a practical solution to 3D dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. In this study, EGSnrc calculated and PAGAT polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of Gamma Knife in homogeneous and inhomogeneous phantoms were compared with eac...

Introduction: Gamma cameras are proposed for online range verification and treatment monitoring in proton therapy.  An Analytical formula was derived and validated for sensitivity of a slit collimator based on the photon fluence concept. Methods: Fluence formulation was generalized for photons distribution function and solved for high-energy point sources. The...

T authors develop a new Monte Carlo-based method for pricing path-dependent options under the variance gamma (VG) model. The gamma bridge sampling method proposed by Avramidis et al. (Avramidis, A. N., P. L’Ecuyer, P. A. Tremblay. 2003. Efficient simulation of gamma and variance-gamma processes. Proc. 2003 Winter Simulation Conf. IEEE Press, Piscataway, NJ, 319–326) and Ribeiro and Webber (Ribe...

This paper presents the statistical inference on the parameters of the Burr type III distribution, when the data are Type-II hybrid censored. The maximum likelihood estimators are developed for the unknown parameters using the EM algorithm method. We provided the observed Fisher information matrix using the missing information principle which is useful for constructing the asymptotic confidence...

The Variance-Gamma model has analytical formulae for the values of European calls and puts. These formulae have to be computed using numerical methods. In general, option valuation may require the use of numerical methods including PDE methods, lattice methods, and Monte Carlo methods. We investigate the use of Monte Carlo methods in the Variance-Gamma model. We demonstrate how a gamma bridge p...

introduction: in single photon emission computed tomography (spect), the projection data used for image reconstruction are distorted by several factors, including attenuation and scattering of gamma rays, collimator structure, data acquisition method, organ motion, and washout of radiopharmaceuticals. all these make reconstruction of a quantitative spect image very difficult. simulation of a sp...