The purpose of this study was to investigate the effect in vitro on macrophage adhesion of Tifell (formocresoleugenol), used as an intracanal medicament and in therapeutic pulpotomies in primary teeth, Macrophages were obtained from Wistar rats. As a test of macrophage phagocytic function the adherence capacity of macrophages to a plastic surface was determined. Assays were carried out in Eppen...

As part of an overall evaluation of possible substitutes for the pulpotomy agent formocresol, this study was initiated to compare the antigenicity of the reaction products of protein with formaldehyde, glutaraldehyde, or dimethylsuberimidate (DMS). Rabbits were injected with rabbit serum albumin (RSA) which had been treated with one of the following solutions: phosphate-buffered saline, 2% glut...

The present investigation was undertaken to clinically and radiograplu’caily observe human p~mary teeth after pulpotomy using one-fifth dilution of formocresol. Seventyseven teeth of 59 ctuTdren, average age seven years, were treated. Seventy teeth were available for follow-up over a peHod varying from 4 to 36 months. The degree of root resorption was evaiuated comparing pairs of treated and ho...

In recent years dyadic combinations of endodontic medicaments have been used increasingly in clinical pediatric dentistry with little regard to the possibility of pharmacological antagonism of the components. In this investigation, a microbial growth inhibition assay was used to determine changes in antimicrobial activity in dyadic mixtures of endodontic medicaments. The combinations assayed we...

Despite modern advances in the prevention of dental caries and the increased understanding of the importance of maintaining the natural primary dentition, many teeth are still lost prematurely. This can lead to malocclusion with aesthetic, phonetic and functional problems that may be transient or permanent. Therefore, maintaining the integrity and health of the oral tissues is the primary objec...

The purpose of this study was to evaluate clinically and radiographically pulpotomies in human primary teeth treated with glutaraldehyde (GA) incorporated into the ZOE subbase without prior 5-min cotton pellet application. Thirty-five cariously exposed primary molars of 35 children 4 to 9 years old were pulpotomized and based with ZOE into which 2% unbuffered GA had been incorporated. Clinical ...