Collagen cleavage, facilitated by collagenases of the matrix metalloproteinase (MMP) family, is crucial for many physiological and pathological processes such as wound healing, tissue remodeling, cancer invasion and organ morphogenesis. Earlier work has shown that mechanical force alters the cleavage rate of collagen. However, experimental results yielded conflicting data on whether applying fo...

Drilling is a widely used machining process. As the hole drilling operation progresses, a drill-bit gradually degrades until it breaks at the end of its life. Replacing a drill-bit after it is breakage can be costly in certain special applications. At the same time an early tool replacement decision may lead to lower tool life utilisation. This calls for methods that enable accurate prediction ...

We have investigated the surface morphology of electrically stressed AlGaN/GaN high electron mobility transistors using atomic force microscopy and scanning electron microscopy after removing the gate metallization by chemical etching. Changes in surface morphology were correlated with degradation in electrical characteristics. Linear grooves formed along the gate edges in the GaN cap layer for...

The interactions of a biodegradable scaffold with cells or living tissues depend on the time-evolution of the nanoscale properties of the scaffold. We present an in situ quantitative study on the early-stage swelling and degradation of poly(lactic-co-glycolic acid) (PLGA). A novel metrology scheme based on force microscopy measurements of the patterns of PLGA nanostructures is developed to char...

Aims: To study force degradation of aspirin and omeprazole simultaneously by RP-HPLC method
 Study design: method was used to measure % degradation.
 Place Duration Study: carried out at center excellence, G.I.D.C., vapi-396195, Gujarat, India between June 2019 march 2020.
 Methodology: A simultaneously. The drugs were subjected various conditions like hydrolysis acid base, Oxida...

development of a numerical model which describes launching of offshore jackets from barge is presented in this paper. in this model, in addition to capabilities of commercial softwares, water entry forces on jacket members and an implicit newmark solution technique are included. the results are in general agreement with other numerical software’s available (sacs). fluid forces acting on jacket ...

in order to design and manufacturing some postharvest equipment, determination of some hydrodynamic properties of crops are necessary. the quality of products in global and local markets can be increased by applying these properties and receive economical benefits. for these purpose, two local varieties of apples in the east azerbaijan province, iran(asheghi and gare yapraq)were selected.ashegh...