Zinc sulfate is a known olfactory toxicant, although its specific effects on the olfactory epithelium of zebrafish are unknown. Olfactory organs of adult zebrafish were exposed to zinc sulfate and, after 2, 3, 5, 7, 10 or 14 days, fish were processed for histological, immunohistochemical, ultrastructural, and behavioral analyses. Severe morphological disruption of the olfactory organ was observ...

ToxR, a transmembrane regulatory protein, has been shown to respond to environmental stimuli. To better understand how the aquatic bacterium Vibrio anguillarum, a fish pathogen, responds to environmental signals that may be necessary for survival in the aquatic and fish environment, toxR and toxS from V. anguillarum serotype O1 were cloned. The deduced protein sequences were 59 and 67% identica...

STUDY OBJECTIVES Colorectal cancer (CRC) is a common cancer in many western countries and is probably caused in part by dietary factors. Southern European countries have lower incidence rates of CRC than many other western countries. It was postulated that, because olive oil is thought to influence bile salt secretion patterns in rats, it may influence the occurrence of CRC. The purpose of this...

An in vivo rainbow trout (Salmo gairdneri) preparation was used to evaluate the gill uptake and toxicokinetics of [3H]fenvalerate ([R,S]-α-cyano-3-phenoxybenzyl [R,S]-2-[4-chloro-phenyl]-3-methylbutyrate), a synthetic pyrethroid insecticide. Fish were exposed to technical-grade fenvalerate (0.28 or 23 ng/L) or an emulsifiable-concentrate formulation (16 ng/L) for 36 to 48 h. No significant effe...

This study evaluated the bioavailability of polycyclic aromatic hydrocarbons (PAHs) in Santos Bay (SB) and adjacent Continental Shelf (SCS) Brazil. Biliary metabolites were measured several fish species to establish a baseline for future monitoring programs. Bile samples from different collected monthly July December 2005 SB, August February 2006 on SCS. Metabolite concentrations determined usi...

Photobacterium damselae subsp. damselae (Pdd) is considered to be an emerging pathogen of marine fish and has also been implicated in cases of histamine food poisoning. In this study, eight strains isolated from mullets of the genera Mugil and Liza captured in the Ligurian Sea were characterized, and a method to detect histamine-producing Pdd from fish samples was developed. The histamine-produ...

Brown trouts (Salmo trutta) from four European high mountain lakes (Norway, the Pyrenees,the Alps and the Tatras) were analyzed for metal and organic pollution, histopathologicalabnormalities and biochemical parameters. Fish from all lakes appeared well nourished withconditioning factors close to unity. Their mean age ranged from 4 to 14 years old inGossenköllesee and Vel’ké...

Anatomic variations in forensic extrahepatic bile ducts is common. Knowledge of extrahepatic bile duct variations is important for surgeons in order to prevent iatrogenic damage during surgery. This study aims to determine the variations in extrahepatic bile ducts among 150 cadavers located at the Kerman Medicine Organization. We performed autopsies on 150 cadavers. Bile ducts were exposed an...

introduction: the present study aims to compare bile and urine samples of a corpse for detection of morphine. methods: in this cross-sectional study, forensic examination of the bodies placed 59 of the 366 referred corpses at the high suspicion of opioid overdose. urine and bile samples of the bodies were analyzed for morphine using thin layer chromatography. results: all samples were taken fro...