نتایج جستجو برای: factor alpha

تعداد نتایج: 998441  

Journal: :Blood 1998
M Narita A E Rudolph J P Miletich A L Schwartz

Blood coagulation factor X plays a pivotal role in the clotting cascade. When administered intravenously to mice, the majority of activated factor X (factor Xa) binds to alpha 2-macroglobulin (alpha 2M) and is rapidly cleared from the circulation into liver. We show here that the low-density lipoprotein receptor-related protein (LRP) is responsible for factor Xa catabolism in vivo. Mice overexp...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2014

Journal: :The Journal of biological chemistry 1989
C B Xue E Eriotou-Bargiota D Miller J M Becker F Naider

An analog of alpha-factor, the Saccharomyces cerevisiae tridecapeptide mating pheromone (Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr), in which the side chains of Lys7 and Gln10 were covalently linked, was synthesized using solid phase methodologies. The yield of the purified cyclic analog cyclo7,10[Nle12]alpha-factor was 30%, and its structure was verified by amino acid analysis, pepti...

Journal: :Proceedings of the National Academy of Sciences 1980

Journal: :Therapeutics and Clinical Risk Management 2008

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