OBJECTIVE To develop additional criteria to predict for successful extubation of very-low-birth-weight infants recovering from respiratory distress syndrome. DESIGN Prospective study. SETTING Neonatal intensive care unit at a university teaching hospital. INTERVENTIONS Infants ready for extubation according to clinical, ventilatory and blood gas criteria were studied. Before extubation, t...

Muitos prematuros extremos necessitam de ventilação assistida. Ao serem extubados, após a resolução da disfunção pulmonar inicial, esses bebês correm risco de haver insucesso na extubação devido a esforço respiratório diminuído, atelectasia, anormalidades da função pulmonar residual ou doença intercorrente. Manter esses bebês extubados diminui a ocorrência de lesão pulmonar e melhora os desfech...

BACKGROUND A substantial proportion of patients with neuromuscular disease (NMD) who undergo positive pressure ventilation via endotracheal intubation for acute respiratory failure fail to pass spontaneous breathing trials and should be considered at high risk for extubation failure. In our study, we prospectively investigated the efficacy of early application of noninvasive ventilation (NIV) c...

INTRODUCTION The extubation period is one of the most challenging aspects for intensive care teams. Timely recognition of the return to spontaneous ventilation is essential for reducing costs, morbidity, and mortality. Several weaning predictors were studied in an attempt to evaluate the outcome of removing ventilatory support. The purpose of this study was to analyze the predictive performance...

OBJECTIVE To evaluate the use of reflex cough PEF as a predictor of successful extubation in neurological patients who were candidates for weaning from mechanical ventilation. METHODS This was a cross-sectional study of 135 patients receiving mechanical ventilation for more than 24 h in the ICU of Cristo Redentor Hospital, in the city of Porto Alegre, Brazil. Reflex cough PEF, the rapid shall...

OBJECTIVE To derive a clinical prediction rule that uses bedside clinical variables to predict extubation failure (reintubation within 48 h) after a successful spontaneous breathing trial. METHODS This prospective observational cohort study was performed at the Northwestern Memorial Hospital in Chicago, Illinois, which is a large tertiary-care university hospital. Among 673 consecutive patien...

case presentation in this report, ultrasound-guided sciatic nerve block was performed in a 25-year-old patient with tetanus to progress his respiratory drive which was decreased due to high dose sedative administration. this procedure accelerates the weaning process and extubation. introduction muscle rigidity and generalized spasm can cause severe pain in patients with tetanus. administration ...