BACKGROUND Health-related quality of life (QoL) has prognostic value in many cancers. A recent study found that the performance of prognostic systems for metastatic colorectal cancer (mCRC) were improvable. We evaluated the independent prognostic value of QoL for overall survival (OS) and its ability to improve two prognostic systems'performance (Köhne and GERCOR models) for patients with mCRC....

Hypertension is one of the deadliest diseases in world. As many as 1 billion people world or 4 adults suffer from this disease. In fact, it estimated that number hypertension sufferers will increase to 1.6 by 2025. Measuring quality life hypertensive patients using Indonesian version EQ5D questionnaire. The purpose study was determine at RSUD Ulin Banjarmasin instrument. This an observational c...

Background: The symptom burden of typical rheumatoid arthritis (RA) symptoms in those at risk for developing RA - positive anti-citrullinated peptide antibodies (ACPA) and musculoskeletal complaints has not been explored. Objectives: To evaluate patient-reported individuals at-risk to develop comparison people with newly diagnosed, early seropositive RA. Methods: Two datasources from the region...

Background Patients with rheumatoid arthritis (RA) who have a difficult-to-treat condition (D2T RA) are often burden to both patients and rheumatologists. Objectives The aim of this study was determine the risk factors for failure treat in refractory conditions find them relevant prevention. Methods RA were treated under treat-to-target (T2T) strategy more than one year picked up. Their backgro...

at present, liver transplantation remains the only curative option for the patients with cirrhosis and end-stage liver diseases. the survival rate and recurrent diseases remain the major issues in the patient post-transplantation. unani medicine is one of the oldest traditional systems of medicine which has been treating chronic liver diseases and cirrhosis (talayyaful-kabid) for centuries. the...

BACKGROUND Traditional endpoints in oncology are based on measuring the tumor size and combining this with a time factor. Current studies with immunotherapy show that even when median survival is unaltered, a significant proportion of patients can achieve prolonged survival. Objective tumor response does not always mean "overall" improvement, especially if toxicity is harsh. Novel agents are si...

BACKGROUND AND OBJECTIVES In the past two decades, an increasing number of nationwide, Swedish Healthcare Quality Registries (QRs) focusing on specific disorders have been initiated, mostly by physicians. Here, we describe the purpose, organization, variables, coverage and completeness of 103 Swedish QRs. METHODS From March to September 2013, we examined the 2012 applications of 103 QRs to th...

Objective: To gain 'first-in-man' evidence that repeated caloric vestibular stimulation (CVS), a non-invasive form of neuro-modulation, can induce a lasting and clinically-relevant reduction in Parkinson's Disease (PD) symptoms. Methods: A 70yr old male, diagnosed with PD 7 years prior to study enrolment, self-administered CVS at home 2x20 minutes per day for three months using a solid-state po...